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Long QT syndrome type 1

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Also Known As:
Ventricular fibrillation with prolonged QT interval
Networked: 14 relevant articles (1 outcomes, 2 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Ackerman, Michael J: 3 articles (05/2013 - 01/2011)
2. Choi, Bum-Rak: 2 articles (01/2015 - 09/2010)
3. Koren, Gideon: 2 articles (01/2015 - 09/2010)
4. Ziv, Ohad: 2 articles (01/2015 - 09/2010)
5. Peng, Xuwen: 2 articles (01/2015 - 09/2010)
6. Kaufman, Elizabeth S: 2 articles (05/2013 - 10/2011)
7. Fressart, Véronique: 2 articles (01/2011 - 12/2006)
8. Denjoy, Isabelle: 2 articles (01/2011 - 12/2006)
9. Berthet, Myriam: 2 articles (01/2011 - 12/2006)
10. Guicheney, Pascale: 2 articles (01/2011 - 12/2006)

Related Diseases

1. Long QT Syndrome
12/28/2006 - "Classic mendelian inheritance ratios were not observed in the offspring of either female carriers of the long-QT syndrome type 1 or male and female carriers of the long-QT syndrome type 2. Among the 1534 descendants, the proportion of genetically affected offspring was significantly greater than that expected according to mendelian inheritance: 870 were carriers of a mutation (57%), and 664 were noncarriers (43%, P<0.001). "
05/01/2013 - "The risk associated with QTcSD was pronounced among patients with long QT syndrome type 1 (hazard ratio 1.55 per 20 ms increment; P<.001), whereas among patients with long QT syndrome type 2, the risk associated with QTcSD was not statistically significant (hazard ratio 0.99; P = .95; P value for QTcSD-by-genotype interaction = .002). "
09/01/2010 - "We have generated transgenic rabbits lacking cardiac slow delayed-rectifier K(+) current [I(Ks); long QT syndrome type 1 (LQT1)] or rapidly activating delayed-rectifier K(+) current [I(Kr); long QT syndrome type 2 (LQT2)]. "
04/01/2013 - "CONCLUSIONS- In this study, we provide evidence that the recessive inheritance of a severe long-QT syndrome type 1 phenotype in the absence of an auditory phenotype may represent a more common pattern of long-QT syndrome inheritance than previously anticipated and that these cases should be treated as a higher-risk long-QT syndrome subset similar to their Jervell and Lange-Nielsen syndrome counterparts. "
06/01/2000 - "Long QT syndrome: ionic basis and arrhythmia mechanism in long QT syndrome type 1."
2. Cardiac Arrhythmias (Arrythmia)
3. Jervell-Lange Nielsen Syndrome (Jervell and Lange-Nielsen Syndrome)
4. Cardiac Sudden Death (Sudden Cardiac Arrest)
5. Tachycardia (Tachyarrhythmias)

Related Drugs and Biologics

1. Potassium