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X-linked sideroblastic anemia

Networked: 46 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Fleming, Mark D: 5 articles (03/2014 - 10/2002)
2. Campagna, Dean R: 4 articles (03/2014 - 03/2006)
3. Harigae, Hideo: 3 articles (02/2015 - 10/2010)
4. Kannengiesser, Caroline: 2 articles (03/2014 - 06/2011)
5. Grandchamp, Bernard: 2 articles (03/2014 - 06/2011)
6. Bottomley, Sylvia S: 2 articles (03/2014 - 02/2010)
7. Kakhlon, Or: 2 articles (03/2010 - 12/2008)
8. Cabantchik, Z Ioav: 2 articles (03/2010 - 12/2008)
9. Breuer, William: 2 articles (03/2010 - 12/2008)
10. Munnich, Arnold: 2 articles (03/2010 - 12/2008)

Related Diseases

1. Ataxia (Dyssynergia)
2. Sideroblastic Anemia
3. Friedreich Ataxia (Friedreich's Ataxia)
01/01/2007 - "The understanding of the role of mitochondrial ferritin in Fe oxidative metabolism may be useful in approaching clinical situations such as the treatment of Friedreich's ataxia, X-linked sideroblastic anemia, and in other neurodegenerative disorders."
05/01/2002 - "The genes responsible for Friedreich ataxia (FRDA) and for X-linked sideroblastic anemia with ataxia are nuclear genes that encode mitochondrial proteins. "
03/01/2010 - "Iron concentrations can rise to toxic levels in mitochondria of excitable cells, often leaving the cytosol iron-depleted, in some forms of neurodegeneration with brain accumulation (NBIA) or following mutations in genes associated with mitochondrial functions, such as ABCB7 in X-linked sideroblastic anemia with ataxia (XLSA/A) or the genes encoding frataxin in Friedreich's ataxia (FRDA). "
01/01/2003 - "Mutations in two such proteins, frataxin and ABCB7, cause Friedreich ataxia and X-linked sideroblastic anemia with ataxia, respectively, rendering other participants in this pathway functional candidates for hereditary ataxia syndromes. "
01/01/2000 - "This chapter considers the most common inherited disorder in individuals of European ancestry (hereditary hemochromatosis), a widespread disease in sub-Saharan populations for which the genetic basis is still uncertain (African dietary iron overload), and several less frequent or rare disorders (juvenile hemochromatosis, atransferrinemia, aceruloplasminemia, hyperferritinemia with autosomal dominant congenital cataract, Friedreich's ataxia, and X-linked sideroblastic anemia with ataxia)."
4. Anemia
5. Iron Overload

Related Drugs and Biologics

1. Iron
2. Heme (Haem)
3. 5-Aminolevulinate Synthetase
4. Adenosine Triphosphate (ATP)
5. frataxin
6. Pyridoxine (Pyridoxin)
7. Apoferritins
8. Mitochondrial Proteins (Mitochondrial Protein)
9. Dietary Iron
10. ATP-Binding Cassette Transporters (ABC Transporters)