Wolffian tumor

A rare, usually benign, neoplasm of the female reproductive system that originates from WOLFFIAN DUCT remnants. The tumors may occur anywhere between the ovaries and vagina.

Also Known As:

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Sex Cord-Gonadal Stromal Tumors (Sex Cord-Stromal Tumor)

Experts

1.	Bonadio, Renata Colombo: 1 article (08/2021)
2.	Carvalho, Filomena Marino: 1 article (08/2021)
3.	Carvalho, Jesus Paula: 1 article (08/2021)
4.	Estevez-Diz, Maria de Pilar: 1 article (08/2021)
5.	Aoki, Yoichi: 1 article (05/2017)
6.	Aoyama, Hajime: 1 article (05/2017)
7.	Inamine, Morihiko: 1 article (05/2017)
8.	Kumagai, Ayumi: 1 article (05/2017)
9.	Matsumoto, Hirofumi: 1 article (05/2017)
10.	Ooyama, Takuma: 1 article (05/2017)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Wolffian tumor:

1.	Imatinib Mesylate (Gleevec)FDA Link 04/01/2008 - "Given the recent reports implying a therapeutic value for Gleevec (Novartis, Stein, Switzerland) (STI-571) in the treatment of Wolffian tumor of the ovary, paraffin immunostain for CD117 (c-kit) was performed that yielded negative results. " 05/01/2017 - "Recurrent female adnexal tumor of probable Wolffian origin treated with debulking surgery, imatinib and paclitaxel/carboplatin combination chemotherapy: A case report."
2.	Paclitaxel (Taxol)FDA LinkGeneric 05/01/2017 - "Recurrent female adnexal tumor of probable Wolffian origin treated with debulking surgery, imatinib and paclitaxel/carboplatin combination chemotherapy: A case report."
3.	Carboplatin (JM8)FDA LinkGeneric 05/01/2017 - "Recurrent female adnexal tumor of probable Wolffian origin treated with debulking surgery, imatinib and paclitaxel/carboplatin combination chemotherapy: A case report."
4.	ParaffinIBA 04/01/2008 - "Given the recent reports implying a therapeutic value for Gleevec (Novartis, Stein, Switzerland) (STI-571) in the treatment of Wolffian tumor of the ovary, paraffin immunostain for CD117 (c-kit) was performed that yielded negative results. "
5.	MethyltransferasesIBA 07/01/2016 - "A female adnexal tumor of probable Wolffian origin showing positive O-6-methylguanine-DNA methyltransferase methylation."
6.	Anastrozole (Arimidex)FDA LinkGeneric 08/01/2021 - "Everolimus plus anastrozole for female adnexal tumor of probable Wolffian origin (FATWO) with STK11 mutation."
7.	EverolimusFDA Link 08/01/2021 - "Everolimus plus anastrozole for female adnexal tumor of probable Wolffian origin (FATWO) with STK11 mutation."
8.	inhibin-alpha subunitIBA 01/01/2001 - "Another gynecological neoplasm that is commonly positive with alpha-inhibin is the so-called female adnexal tumor of probable wolffian origin, and, therefore, the antibody is of no value in the distinction of this neoplasm from a sex cord-stromal tumor, tumors that are often in the differential diagnosis."

Therapies and Procedures

1.	Radiotherapy 09/15/1985 - "The case history of a woman with a "female adnexal tumor of probable Wolffian origin" is described in which the neoplasm recurred three times during a 16-year interval and responded with prolonged remission after repeated surgical excision and radiotherapy. "
2.	Combination Drug Therapy (Combination Chemotherapy) 05/01/2017 - "Recurrent female adnexal tumor of probable Wolffian origin treated with debulking surgery, imatinib and paclitaxel/carboplatin combination chemotherapy: A case report."