Witkop syndrome

Autosomal dominant disorder characterized by nail dysplasia and congenitally missing permanent teeth; associated with mutations in the MSX1 gene

Also Known As:

Dysplasia of nails with hypodontia; Nail Dysplasia With Hypodontia; Tooth and nail syndrome; Tooth-And-Nail Syndrome

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Witkop syndrome

Drugs and Important Biological Agents (IBA) related to Witkop syndrome:

1.	2-(4-toluidino)-6-naphthalenesulfonic acid (TNS)IBA 01/01/2010 - "This is the first report of a rare genetic tooth and nail syndrome (TNS) diagnosed in a 14-year-old Caucasian girl with a complete absence of the permanent dentition and, additionally, reduced total and lumbar spine bone mineral density (BMD). " 07/01/2001 - "Witkop syndrome, also known as tooth and nail syndrome (TNS), is a rare autosomal dominant disorder. "
2.	Nonsense Codon (Nonsense Mutation)IBA 07/01/2001 - "A nonsense mutation in MSX1 causes Witkop syndrome."

1.	Orthodontics 03/01/2008 - "Witkop tooth and nail syndrome and orthodontics."