Satoyoshi syndrome

Also Known As:

Komuragaeri Disease; Muscle Spasms, Intermittent, With Alopecia, Diarrhea, And Skeletal Abnormalities; Muscle spasms, intermittent with alopecia, diarrhea, and skeletal abnormalities

Networked: 18 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Spasm (Spasms)
2.	Diarrhea
3.	Alopecia (Baldness)
4.	Rickets (Rachitis)
5.	Autoimmune Diseases (Autoimmune Disease)

Experts

1.	Solera, Javier: 2 articles (01/2019 - 10/2015)
2.	de Cabo, Carlos: 2 articles (01/2019 - 10/2015)
3.	Bledsoe, Ian O: 1 article (07/2020)
4.	Solís-García Del Pozo, Julián: 1 article (01/2019)
5.	Couto, Christian Marques: 1 article (04/2017)
6.	Hora, Thiago Falcão: 1 article (04/2017)
7.	Montanaro, Vinícius Viana Abreu: 1 article (04/2017)
8.	Ribas, Flavio Diniz: 1 article (04/2017)
9.	Aghoram, Rajeshwari: 1 article (01/2016)
10.	Kannoth, Sudheeran: 1 article (01/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Satoyoshi syndrome:

1.	Adrenal Cortex Hormones (Corticosteroids)IBA 01/01/2019 - "Corticosteroids was the most widely treatment employed with the best results in Satoyoshi syndrome. " 04/01/2017 - "Diagnosis of Satoyoshi syndrome was made after extensive investigation; improvement was achieved with corticosteroids and azathioprine. " 06/24/2003 - "Improvement of Satoyoshi syndrome with tacrolimus and corticosteroids."
2.	GlucocorticoidsIBA 04/01/2003 - "Satoyoshi syndrome in a Caucasian girl improved with glucocorticoids--a clinical report." 01/01/1991 - "The association of autoimmune disorders and the responsiveness of all clinical features to glucocorticoid suggest that an autoimmune process is involved in the pathogenesis of generalized komuragaeri disease." 01/01/1991 - "[A case of generalized komuragaeri disease (Satoyoshi disease) treated with glucocorticoid]."
3.	AutoantibodiesIBA 01/01/2023 - "More studies including systematic determination of autoantibodies in all patients with Satoyoshi syndrome will help us advance in our understanding of this disease." 01/01/2014 - "The patient's histological findings and positivity for autoantibodies indicated the presence of immunological abnormalities in this case of Satoyoshi syndrome. " 01/01/2023 - "Satoyoshi syndrome is associated with other autoimmune diseases and a variety of autoantibodies. "
4.	Botulinum Toxins (Botulinum Toxin)IBA 01/01/1994 - "Masticatory muscle spasm in a non-Japanese patient with Satoyoshi syndrome successfully treated with botulinum toxin." 07/01/2020 - "Phenomenology of Muscle Spasms in Satoyoshi Syndrome and Treatment With Botulinum Toxin Injections."
5.	Antinuclear AntibodiesIBA 11/01/2014 - "In our opinion all patients will alopecia areata (in particular alopecia totalis) should be inquired about muscle spasms and diarrhea and tested for antinuclear antibodies to decrease the risk of missing Satoyoshi syndrome." 08/01/2008 - "Satoyoshi syndrome with autoimmune features (high levels of antinuclear antibody and antibodies to thyroid tissue) and malabsorption due to eosinophilic enteritis. "
6.	AntibodiesIBA 03/01/2004 - "Glutamic acid decarboxylase antibodies in Satoyoshi syndrome." 08/01/2008 - "Satoyoshi syndrome with autoimmune features (high levels of antinuclear antibody and antibodies to thyroid tissue) and malabsorption due to eosinophilic enteritis. "
7.	Therapeutic UsesIBA 01/01/1984 - "[Positive therapeutic effect of diacarb in the syndrome of progressive muscle spasms, alopecia and diarrhea (Satoyoshi syndrome)]."
8.	Tacrolimus (Prograf)FDA LinkGeneric 06/24/2003 - "Improvement of Satoyoshi syndrome with tacrolimus and corticosteroids."
9.	Vitamin D FDA LinkGeneric 05/01/2013 - "We report a case of Satoyoshi syndrome misdiagnosed as vitamin D-dependent rickets for several years."
10.	Midazolam (Versed)FDA LinkGeneric 07/01/1998 - "It remains to be clarified whether midazolam administration induces NMS in Satoyoshi syndrome. "

Therapies and Procedures

1.	Therapeutics 11/01/2014 - "We also suggest that two subtypes of the disorder should be distinguished, the ANA-positive Satoyoshi syndrome with generally good response to systemic glucocorticosteroid therapy and the ANA-negative Satoyoshi with less favorable prognosis. " 09/01/1996 - "This is the first report of gammaglobulin therapy of Satoyoshi syndrome. " 09/01/1996 - "Intravenous gammaglobulin therapy of Satoyoshi syndrome."
2.	Plasmapheresis 01/01/2016 - "In this paper, we report the first case of adult-onset Satoyoshi syndrome from India and the clinical and electrophysiological response to plasmapheresis. " 01/01/2016 - "Adult-onset Satoyoshi syndrome and response to plasmapheresis."
3.	Injections 07/01/2020 - "Phenomenology of Muscle Spasms in Satoyoshi Syndrome and Treatment With Botulinum Toxin Injections."