|1.||Satoh, Jun-Ichi: 5 articles (12/2015 - 08/2011)|
|2.||Peltonen, Leena: 5 articles (01/2009 - 09/2002)|
|3.||Yagishita, Saburo: 4 articles (12/2015 - 08/2011)|
|4.||Jinnai, Kenji: 4 articles (12/2015 - 08/2011)|
|5.||Ishida, Tsuyoshi: 4 articles (12/2015 - 08/2011)|
|6.||Arai, Nobutaka: 4 articles (12/2015 - 08/2011)|
|7.||Arima, Kunimasa: 4 articles (12/2015 - 08/2011)|
|8.||Colonna, Marco: 4 articles (05/2015 - 08/2003)|
|9.||Hakola, Panu: 4 articles (07/2014 - 08/2003)|
|10.||Paloneva, Juha: 4 articles (09/2007 - 09/2002)|
01/01/2013 - "Compared with the control subjects, PLOSL patients with moderate or severe dementia were impaired in both learning trials and delayed recall on the 10-word list-learning test. "
01/01/2015 - "TREM2 and TYROBP are causal genes for Nasu-Hakola disease (NHD), a rare autosomal recessive disease characterized by bone lesions and early-onset progressive dementia. "
11/01/2014 - "Homozygous mutations in TREM2 cause Nasu-Hakola disease, a rare recessive form of dementia. "
03/15/2013 - "PLOSL is a unique disease clinically characterized by a progressive presenile frontal-lobe dementia and multiple cystic bone lesions, typically leading to fractures of the limbs in the third decade of life. "
01/01/2008 - "DAP12 is a microglial signaling protein expressed around birth, mutations of which in the human induces the Nasu-Hakola disease, characterized by early dementia. "
10/01/2014 - "Membranous lipodystrophy, also known as Nasu-Hakola disease, is a rare hereditary condition with manifestations in the nervous and skeletal systems. "
07/01/2003 - "Membranous lipodystrophy is known as Nasu-Hakola disease. "
07/01/2003 - "Membranous lipodystrophy (Nasu-Hakola disease) presenting an unusually benign clinical course."
07/01/2000 - "A case of membranous lipodystrophy (Nasu-Hakola disease; NHD) associated with palilalia was reported. "
10/01/1995 - "A case of membranous lipodystrophy (Nasu-Hakola disease) with unique MRI findings."
|4.||Bone Cysts (Bone Cyst)
12/31/2015 - "Nasu-Hakola disease (NHD) is a rare autosomal recessive neuropsychiatric disorder characterized by bone cysts, fractures, and cognitive impairment. "
01/01/2013 - "None of these 3 patients had a typical clinical presentation of PLOSL: they presented with behavioral change and subsequent cognitive impairment and motor features but without any bone cysts or bone-associated phenotypes. "
12/01/2015 - "Nasu-Hakola disease (NHD) is a rare autosomal recessive disorder, characterized by formation of multifocal bone cysts and development of leukoencephalopathy, caused by genetic mutations of either DNAX-activation protein 12 (DAP12) or triggering receptor expressed on myeloid cells 2 (TREM2). "
05/01/2015 - "Mutations of Q33X, Y38C and T66M cause Nasu-Hakola disease (NHD) which is characterized by early onset of dementia and bone cysts. "
10/01/2014 - "The observation of a small bone cyst in our patient supports the hypothesis that hereditary diffuse leukoencephalopathy with neuroaxonal spheroids and polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy may belong to a spectrum of overlapping phenotypes. "
|5.||Alzheimer Disease (Alzheimer's Disease)
12/01/2014 - "Certain mutations in DAP12 and TREM-2 manifest into a disorder named polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy, and newly identified TREM-2 variants confer a significant increase in risk of developing Alzheimer's disease. "
01/01/2006 - "Clinical, radiological, genetic, and histopathological features of PLOSL disease are discussed in the differential diagnosis of presenile dementia and basal ganglia calcification."
12/15/2004 - "Its mutation in humans induces Nasu-Hakola disease, characterized by presenile dementia and demyelinization. "
10/23/2015 - "These findings reveal a link between two Alzheimer disease risk factors and may provide important clues to the pathogenesis of Nasu-Hakola disease and other neurodegenerative disorders. "
10/01/2015 - "Nasu-Hakola disease (NHD) is a form of presenile dementia associated with sclerosing leukoencephalopathy and polycystic lipomembranous osteodysplasia. "
|1.||Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy