Purpura simplex

A form of purpura affecting the extremities. ECCHYMOSIS upon slight trauma and MENORRHAGIA are also common. OMIM: 179000

Also Known As:

Hereditary familial purpura simplex

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

1.	Hemorrhagic Disorders (Hemorrhagic Diathesis)
2.	Cushing Syndrome

Drugs and Important Biological Agents (IBA) related to Purpura simplex:

1.	Factor Xa (Coagulation Factor Xa)IBA 08/01/1958 - "[Grave transitory hemorrhagic diathesis in pregnancy; thrombokinase intoxication caused by premature detachment of the placenta in familial purpura simplex]."
2.	Cortisone FDA Link 09/03/1955 - "Familial hereditary purpura simplex with Schönlein-Henoch syndrome; response to corticotropin (ACTH), cortisone, and antihistaminics."
3.	Aminoglutethimide (Cytadren)FDA Link 10/15/1994 - "Capillaritis (purpura simplex) associated with use of aminoglutethimide in Cushing's syndrome."
4.	Adrenocorticotropic Hormone (ACTH)FDA Link 09/03/1955 - "Familial hereditary purpura simplex with Schönlein-Henoch syndrome; response to corticotropin (ACTH), cortisone, and antihistaminics."
5.	HLA-DQA1 antigen (HLA DQA1)IBA 02/01/2002 - "On the other hand, the gene frequencies of HLA-DQA10302 were 6.7% and 19% in the AP group and the control group respectively; a significant difference between them was seen (chi square=9.786, P<0.01); (2)The gene frequencies of both DQA10301 and DQA1*0302 in the cutaneous purpura simplex cases and the controls were not significantly different (P>0.05). "