Blue diaper syndrome

Also Known As:

Hypercalcemia, familial, with nephrocalcinosis and indicanuria

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Eye Abnormalities: 95
    - Blue diaper syndrome: 5
- Inborn Genetic Diseases: 11939
  - Inborn Errors Metabolism: 1162
    - Inborn Errors Amino Acid Metabolism: 1
      - Blue diaper syndrome: 5
Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
Eye Diseases: 3522
- Eye Abnormalities: 95
  - Blue diaper syndrome: 5
Urogenital Diseases: 126
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Tryptophan: 6733
      - Blue diaper syndrome: 5
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Tryptophan: 6733
        Blue diaper syndrome: 5

Related Diseases

1.	Hartnup Disease
2.	Hyperammonemia
3.	Hyperargininemia
4.	Vitiligo
5.	Huntington Disease (Huntington's Disease)

Experts

1.	Chairoungdua, Arthit: 2 articles (04/2005 - 01/2002)
2.	Endou, Hitoshi: 2 articles (04/2005 - 01/2002)
3.	Kanai, Yoshikatsu: 2 articles (04/2005 - 01/2002)
4.	Kim, Do Kyung: 2 articles (04/2005 - 01/2002)
5.	Choi, Bong Kyu: 1 article (04/2005)
6.	Jung, Kyu Yong: 1 article (04/2005)
7.	Kim, In Jin: 1 article (04/2005)
8.	Kim, Jong-Keun: 1 article (04/2005)
9.	Lee, Seoul: 1 article (04/2005)
10.	Park, Kyung Jin: 1 article (04/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Blue diaper syndrome:

1.	Aromatic Amino Acids (Aromatic Amino Acid)IBA 01/01/2002 - "Because human TAT1 is proposed to be crucial to the efficient absorption of aromatic amino acids from intestine and kidney, its defect could be involved in the disruption of aromatic amino-acid transport, such as in blue diaper syndrome."
2.	Neutral Amino AcidsIBA 04/01/2005 - "Because LAT2 and TAT1 are essential to the efficient absorption of neutral amino acids from the kidney, their defects might be involved in the pathogenesis of disorders caused by a disruption in amino acid absorption such as blue diaper syndrome."
3.	Acetic Acid (Vinegar)FDA LinkGeneric 01/01/2022 - "Urine enrichment pathway analysis showed that 4 metabolic pathways, including Aromatic L-Amino Acid Decarboxylase, Vitiligo, Blue Diaper Syndrome and Hyperargininemia, the core metabolites in these pathways including dopamine, 5-hydroxyindole acetic acid and arginine. "
4.	Niacin (Nicotinic Acid)FDA LinkGeneric 10/01/1999 - "Niacin is also related to the following diseases: Hartnup disease; blue diaper syndrome; tryptophanuria; hydroxykynureninuria; xanthurenic aciduria; Huntington's disease."
5.	Dopamine (Intropin)FDA LinkGeneric 01/01/2022 - "Urine enrichment pathway analysis showed that 4 metabolic pathways, including Aromatic L-Amino Acid Decarboxylase, Vitiligo, Blue Diaper Syndrome and Hyperargininemia, the core metabolites in these pathways including dopamine, 5-hydroxyindole acetic acid and arginine. "
6.	Aromatic-L-Amino-Acid DecarboxylasesIBA 01/01/2022 - "Urine enrichment pathway analysis showed that 4 metabolic pathways, including Aromatic L-Amino Acid Decarboxylase, Vitiligo, Blue Diaper Syndrome and Hyperargininemia, the core metabolites in these pathways including dopamine, 5-hydroxyindole acetic acid and arginine. "
7.	Arginine (L-Arginine)FDA Link 01/01/2022 - "Urine enrichment pathway analysis showed that 4 metabolic pathways, including Aromatic L-Amino Acid Decarboxylase, Vitiligo, Blue Diaper Syndrome and Hyperargininemia, the core metabolites in these pathways including dopamine, 5-hydroxyindole acetic acid and arginine. "
8.	Amino Acids FDA Link 04/01/2005 - "Because LAT2 and TAT1 are essential to the efficient absorption of neutral amino acids from the kidney, their defects might be involved in the pathogenesis of disorders caused by a disruption in amino acid absorption such as blue diaper syndrome."
9.	IminoglycinuriaIBA 07/01/1992 - "The disorders were categorized into three types of transport defects, namely, brush-border membrane of epithelial cells of small intestine and kidney tubules (Hartnup disease, blue diaper syndrome, cystinuria, iminoglycinuria and lysine malabsorption syndrome), basolateral membrane (lysinuric protein intolerance) and membrane of intracellular organelles (cystinosis and hyperornitinemia-hyperammonemia-homocitrullinuria syndrome). "
10.	5-hydroxyindoleIBA 01/01/2022 - "Urine enrichment pathway analysis showed that 4 metabolic pathways, including Aromatic L-Amino Acid Decarboxylase, Vitiligo, Blue Diaper Syndrome and Hyperargininemia, the core metabolites in these pathways including dopamine, 5-hydroxyindole acetic acid and arginine. "