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type 2 Crigler Najjar syndrome

Crigler Najjar syndrome, type 2
Also Known As:
Crigler Najjar syndrome, type 2
Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Araki, Jun: 2 articles (10/2006 - 09/2004)
2. Kaito, Masahiko: 2 articles (10/2006 - 09/2004)
3. Kobayashi, Yoshinao: 2 articles (10/2006 - 09/2004)
4. Peng, Yun-sheng: 1 article (08/2013)
5. Zhou, Zhi-ming: 1 article (08/2013)
6. Tu, Chuan-qing: 1 article (08/2013)
7. Chen, Qun-rong: 1 article (08/2013)
8. Sun, Shun-chang: 1 article (08/2013)
9. Lohse, Peter: 1 article (05/2012)
10. Nampoothiri, Sheela: 1 article (05/2012)

Related Diseases

1. Kernicterus
2. Gilbert Disease
09/01/2004 - "To clarify the incidence of this gene mutation in the Japanese population, the presence of UGT1A1 mutation was investigated in a group of Japanese patients with Crigler-Najjar syndrome type 2 (CNS2) and Gilbert's syndrome (GS), as well as in healthy anicteric subjects. "
10/01/2006 - "Gilbert's syndrome (GS) and Crigler Najjar syndrome type 2 (CNS-II) are characterized by unconjugated hyperbilirubinemia due to reduced enzymatic activity of UGT1A1. "
01/01/2006 - "The objective was to determine the frequencies of the following mutations in the UGT1A1 gene: A(TA)7TAA (the most common cause of Gilbert syndrome in Caucasians), G71R (more common in the Japanese and Taiwanese population), and G493R (described in a homozygous Malay woman with Crigler-Najjar syndrome type 2) in a group of Malaysian babies with hyperbilirubinemia and a group of normal controls. "
08/01/2013 - "Based on the UGT1A1 gene mutations and level of total serum bilirubin, 44 patients were diagnosed with Gilbert syndrome, and 2 were diagnosed with Crigler-Najjar syndrome type 2. The level of total serum bilirubin is correlated with the number of UGT1A1 gene mutations as well as their heterozygous or homozygous status."
06/01/1990 - "Serum bilirubin fractions were determined by a newly developed, high performance liquid chromatography method in 23 healthy subjects, and in 15 patients with Gilbert's syndrome, five with type 2 Crigler-Najjar syndrome, seven with hemolytic disorders, and 26 with neonatal jaundice. "
3. Hyperbilirubinemia
4. beta-Thalassemia (Cooley's Anemia)
5. Neonatal Jaundice

Related Drugs and Biologics

1. Bilirubin
2. Carbon Monoxide