Ehlers-Danlos syndrome type 1

Also Known As:

Ehlers-Danlos Syndrome, Severe Classic Type; Ehlers-Danlos Syndrome, Type I; Ehlers-Danlos syndrome, Gravis type; Ehlers-Danlos syndrome, classic severe form

Networked: 7 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Cardiovascular Diseases: 91362
- Vascular Diseases: 15138
  - Hemostatic Disorders: 250
    - Ehlers-Danlos Syndrome: 799
      - Ehlers-Danlos syndrome type 1: 7
Hemic and Lymphatic Diseases: 6
- Hematologic Diseases: 3366
  - Hemorrhagic Disorders: 702
    - Hemostatic Disorders: 250
      - Ehlers-Danlos Syndrome: 799
        Ehlers-Danlos syndrome type 1: 7
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Skin Abnormalities: 159
    - Ehlers-Danlos Syndrome: 799
      - Ehlers-Danlos syndrome type 1: 7
- Inborn Genetic Diseases: 11939
  - Genetic Skin Diseases: 47
    - Ehlers-Danlos Syndrome: 799
      - Ehlers-Danlos syndrome type 1: 7
Skin and Connective Tissue Diseases
- Skin Diseases: 13127
  - Skin Abnormalities: 159
    - Ehlers-Danlos Syndrome: 799
      - Ehlers-Danlos syndrome type 1: 7
  - Genetic Skin Diseases: 47
    - Ehlers-Danlos Syndrome: 799
      - Ehlers-Danlos syndrome type 1: 7
- Connective Tissue Diseases: 3269
  - Collagen Diseases: 754
    - Ehlers-Danlos Syndrome: 799
      - Ehlers-Danlos syndrome type 1: 7

Related Diseases

1.	Mitral Valve Insufficiency (Mitral Regurgitation)
2.	Atrial Fibrillation

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ehlers-Danlos syndrome type 1:

1.	Collagen Type III (Type III Collagen)IBA 07/01/1987 - "Ehlers-Danlos syndrome type I: a clinical and ultrastructural study of a family with reduced amounts of collagen type III." 07/01/1987 - "To our knowledge, this is the first report of a type III collagen deficiency in Ehlers-Danlos syndrome type I. The findings in this family, especially the pronounced bruising tendency, illustrate the heterogeneity within type I EDS."
2.	CollagenIBA 09/01/1988 - "Morphometric study of cauliflower collagen fibrils in Ehlers-Danlos syndrome type I."
3.	Collagen Type V (Type V Collagen)IBA 02/01/1998 - "Mutations of the alpha2(V) chain of type V collagen impair matrix assembly and produce ehlers-danlos syndrome type I." 06/01/1996 - "The gene encoding collagen alpha1(V)(COL5A1) is linked to mixed Ehlers-Danlos syndrome type I/II."
4.	Zinc Sulfate FDA Link 11/01/1979 - "Oral administration of zinc sulfate did not improve the clinical conditions in two patients with Ehlers-Danlos-Syndrome type I. Zinc levels in serum and hair were normal before and during treatment."
5.	ZincIBA 11/01/1979 - "Oral administration of zinc sulfate did not improve the clinical conditions in two patients with Ehlers-Danlos-Syndrome type I. Zinc levels in serum and hair were normal before and during treatment."
6.	alpha2 Subunit Collagen Type IIBA 12/01/1991 - "Exclusion of COL1A1, COL1A2, and COL3A1 genes as candidate genes for Ehlers-Danlos syndrome type I in one large family."

Therapies and Procedures

1.	Electric Countershock (Cardioversion) 07/01/1999 - "We describe the case of a 63-year-old man with Ehlers-Danlos syndrome type I or II, mitral regurgitation and atrial fibrillation who was managed successfully with mitral valve repair and surgical cardioversion."
2.	Oral Administration 11/01/1979 - "Oral administration of zinc sulfate did not improve the clinical conditions in two patients with Ehlers-Danlos-Syndrome type I. Zinc levels in serum and hair were normal before and during treatment."