Keratosis palmoplantaris striata 1

Also Known As:

Keratoderma, Palmoplantar, Striate Form I; Keratoderma, palmoplantar striate form 1; Keratosis Palmoplantaris Striata I; Striate Palmoplantar Keratoderma I; Striate palmoplantar keratoderma 1

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Genetic Skin Diseases: 47
    - Palmoplantar Keratoderma: 313
      - Keratosis palmoplantaris striata 1: 1
Skin and Connective Tissue Diseases
- Skin Diseases: 13127
  - Keratosis: 706
    - Palmoplantar Keratoderma: 313
      - Keratosis palmoplantaris striata 1: 1
  - Genetic Skin Diseases: 47
    - Palmoplantar Keratoderma: 313
      - Keratosis palmoplantaris striata 1: 1

Related Diseases

1.	Hypersensitivity (Allergy)
2.	Dermatitis

Experts

1.	Backel, Katherine A: 1 article (01/2020)
2.	Casal, Margret L: 1 article (01/2020)
3.	Jagannathan, Vidhya: 1 article (01/2020)
4.	Kiener, Sarah: 1 article (01/2020)
5.	Leeb, Tosso: 1 article (01/2020)
6.	Mauldin, Elizabeth A: 1 article (01/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Keratosis palmoplantaris striata 1:

1.	Desmoglein 1IBA 01/01/2020 - "This was located in the DSG1 gene encoding desmoglein 1. Heterozygous monoallelic DSG1 variants have been reported in human patients with striate palmoplantar keratoderma I (SPPK1), while biallelic DSG1 loss of function variants in humans lead to a more pronounced condition termed severe dermatitis, multiple allergies, and metabolic wasting (SAM) syndrome. "