Marie Unna congenital hypotrichosis

Congenital hypotrichosis characterized by little or no eyebrows, eyelashes, or body hair at birth, followed by the development of coarse, wiry, twisted hair in early childhood which progresses to ALOPECIA. Two genetically distinct forms exist; type I is caused by mutations in the hair growth associated (HR) gene. OMIM: 146550

Also Known As:

Hypotrichosis, Marie Unna type; Marie Unna hereditary hypotrichosis

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Skin and Connective Tissue Diseases
- Skin Diseases: 13127
  - Hair Diseases: 36
    - Hypotrichosis: 170
      - Marie Unna congenital hypotrichosis: 2

Experts

1.	Choi, Jee-Hyun: 1 article (01/2018)
2.	Choi, Keonwoo: 1 article (01/2018)
3.	Kim Yoon, Sungjoo: 1 article (01/2018)
4.	Kim, Eunmin: 1 article (01/2018)
5.	Kim, Injung: 1 article (01/2018)
6.	Kim, Jeong-Ki: 1 article (01/2018)
7.	Lee, Hwa-Young: 1 article (01/2018)
8.	Park, Jongkeun: 1 article (01/2018)
9.	Baek, In Cheol: 1 article (06/2009)
10.	Cha, Dal-Sun: 1 article (06/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Marie Unna congenital hypotrichosis:

1.	5' Untranslated Regions (5' UTR)IBA 01/01/2018 - "We also found that this regulation was disrupted in a mutant Hr 5' UTR that has a mutation responsible for Marie Unna hereditary hypotrichosis (MUHH) in both mice and humans. " 06/01/2009 - "Both mutations were in the uATG codon of the second uORF in the 5' UTR and corresponded to the mutations identified in Marie Unna Hereditary Hypotrichosis (MUHH) patients. "
2.	Codon (Codons)IBA 06/01/2009 - "Both mutations were in the uATG codon of the second uORF in the 5' UTR and corresponded to the mutations identified in Marie Unna Hereditary Hypotrichosis (MUHH) patients. "