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Familial primary gastric lymphoma

A rare familial gastric lymphoma of the mucosa-associated lymphoid tissue type (MALT) that originates from B-LYMPHOCYTES. A germline mutation in the BCL10 gene has been identified. OMIM: 137245
Also Known As:
Gastric Lymphoma, Primary; Gastric lymphoma; Primary gastric lymphoma
Networked: 352 relevant articles (23 outcomes, 33 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Familial primary gastric lymphoma
2. Lymphoma (Lymphomas)
3. Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
4. Neoplasms (Cancer)
5. Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)

Experts

1. Uno, Takashi: 4 articles (11/2014 - 04/2006)
2. Chott, A: 4 articles (07/2002 - 01/2000)
3. Raderer, M: 4 articles (07/2002 - 01/2000)
4. Nakamura, Shigeo: 3 articles (08/2019 - 09/2000)
5. Fischbach, W: 3 articles (04/2011 - 11/2000)
6. Tuo, Shuai: 3 articles (06/2010 - 02/2010)
7. Yang, Bo: 3 articles (06/2010 - 02/2010)
8. Zhang, Ning: 3 articles (06/2010 - 02/2010)
9. Bjelović, M: 3 articles (01/2007 - 01/2000)
10. Osterreicher, C: 3 articles (07/2002 - 05/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Familial primary gastric lymphoma:
1. Rituximab (Mabthera)FDA Link
2. Anti-Bacterial Agents (Antibiotics)IBA
3. AntigensIBA
4. HLA-DR Antigens (HLA-DR)IBA
5. Doxorubicin (Adriamycin)FDA LinkGeneric
04/01/1995 - "We have prospectively evaluated a stomach conservation strategy in histologically aggressive gastric lymphoma, using primary adriamycin-containing chemotherapy, followed by involved-field radiotherapy in patients with limited disease. "
03/01/2005 - "The authors describe the unusual association between diffuse B-cell gastric lymphoma and myotonic dystrophy, the most common form of adult muscular dystrophy, and sudden atrial fibrillation following one cycle of doxorubicin-based chemotherapy in the same patient. "
07/01/2002 - "Recent data suggest that chemotherapy with the cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) regimen is a highly effective treatment for localised primary gastric lymphoma of diffuse large B-cell histology (DLBCL). "
10/01/1986 - "The principal treatment plan consisted of surgical resection of the gastric lymphoma (n = 36) where feasible, followed by radiation therapy of the whole abdomen (n = 23) with a boosting dose to the stomach-bed to 3700 cGy, and/or chemotherapy using mainly the CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) regimen as an adjuvant (n = 7), or CHOP plus other drugs for advanced disease. "
06/01/2005 - "CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) followed by radiotherapy is regarded as standard care for localized aggressive lymphoma; however, prospective confirmation of its applicability to localized primary gastric lymphoma is inadequate, and most patients in Japan have been initially treated with gastrectomy. "
6. Cyclophosphamide (Cytoxan)FDA LinkGeneric
7. Vincristine (Oncovin)FDA LinkGeneric
8. Prednisone (Sone)FDA LinkGeneric
9. Monoclonal AntibodiesIBA
10. bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Radiotherapy
4. VAP-cyclo protocol
5. Gastrectomy