|1.||Bernard, Pascal: 2 articles (04/2012 - 07/2006)|
|2.||Harley, Vincent R: 2 articles (04/2012 - 07/2006)|
|3.||Beuschlein, Felix: 2 articles (02/2009 - 02/2007)|
|4.||McCabe, Edward R B: 2 articles (07/2006 - 09/2004)|
|5.||Fang, Zongjuan: 2 articles (10/2003 - 09/2002)|
|6.||Gurates, Bilgin: 2 articles (10/2003 - 09/2002)|
|7.||Bulun, Serdar E: 2 articles (10/2003 - 09/2002)|
|8.||Sebastian, Siby: 2 articles (10/2003 - 09/2002)|
|9.||Yang, Sijun: 2 articles (10/2003 - 09/2002)|
|10.||Tamura, Mitsutoshi: 2 articles (10/2003 - 09/2002)|
|1.||Granulosa Cell Tumor
|2.||Hypogonadism (Hypergonadotropic Hypogonadism)
07/01/2015 - "To analyze the DAX1 (NR0B1) (dosage-sensitive sex reversal-adrenal hypoplasia congenita (AHC) critical region on the X chromosome gene 1) gene in two Chinese families with AHC and hypogonadotrophic hypogonadism (HHG). "
03/01/2008 - "Mutations of DSS (dosage sensitive sex reversal)-AHC critical region on the X chromosome, gene 1 DAX-1(NROB1)] results in X-linked adrenal hypoplasia congenita (AHC) and hypogonadotropic hypogonadism (HHG). "
07/01/2006 - "Mutations in the DAX1 (Dosage-sensitive sex reversal-Adrenal hypoplasia congenita (AHC) critical region on the X chromosome gene 1; NR0B1) cause X-linked AHC, a disease characterized by primary adrenal failure in infancy and hypogonadotropic hypogonadism. "
09/01/2004 - "DAX1 (dosage sensitive sex reversal (DSS), adrenal hypoplasia congenita (AHC) critical region on the X chromosome, gene 1) encoded by the gene NR0B1, is an unusual orphan nuclear receptor that when mutated causes AHC with associated hypogonadotropic hypogonadism (HH), and when duplicated causes DSS. "
01/01/2004 - "Nr0b1/NR0B1 expression at appropriate dosages is required for normal steroidogenic axis development: mutation of the human ortholog, NR0B1, results in adrenal hypoplasia congenita and hypogonadotropic hypogonadism; and duplication or transgenic overexpression in humans or mice, respectively, results in XY phenotypic females, a phenotype known as dosage sensitive sex-reversal. "
|3.||Wilms Tumor (Wilm's Tumor)
09/01/2002 - "Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome gene 1 (DAX-1) inhibits SF-1-mediated induction of MIS and other steroidogenic genes, whereas Wilms' tumor suppressor gene (WT1) augments SF-1-mediated MIS expression. "
02/01/2007 - "A variety of transcription factors including Wilms tumor gene (Wt-1), steroidogenic factor 1 (Sf-1), dosage-sensitive sex reversal, adrenal hypoplasia congenita on the X-chromosome, Gene 1 (Dax-1), and pre-B-cell transcription factor 1 (Pbx1) have been defined as necessary for regular adrenocortical development. "
10/31/2003 - "We also show herein that the stimulation of P450arom promoter activity by SF-1 in ovarian granulosa, testicular Sertoli and JEG-3 choriocarcinoma cells is inhibited by two transcription factors, Wilms' tumor suppressor gene (WT1) and dosage sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome gene 1 (DAX-1). "
02/01/2009 - "The regulation of CITED2 and PBX1 by steroidogenic factor-1 (SF-1) and dosage-sensitive sex reversal, adrenal hypoplasia congenital, critical region on the X chromosome, gene-1 (DAX1) was evaluated in NCI-H295R human adrenocortical tumor cells by studying promoter regulation. "
06/01/2004 - "Therefore, we examined AKR1B1 gene expression in human fetal adrenals, adrenocortical cell line, and tumors and compared the results with the expression of steroidogenic genes (StAR and CYP11A) and regulators of adrenal cortex development [steroidogenic factor-1 (SF-1) and dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1)]. "
01/01/2009 - "Role of dosage-sensitive sex reversal, adrenal hypoplasia congenita, critical region on the X chromosome, gene 1 in protein kinase A- and protein kinase C-mediated regulation of the steroidogenic acute regulatory protein expression in mouse Leydig tumor cells: mechanism of action."
|5.||Gonadal Dysgenesis (Gonadal Agenesis)
04/01/2012 - "Human DAX1 duplications cause dosage-sensitive sex reversal (DSS) whereby chromosomally XY individuals can develop as females due to gonadal dysgenesis. "
01/01/2010 - "Sex reversal due to duplication of the Xp21 dosage-sensitive sex reversal locus results in XY females with gonadal dysgenesis. "
|2.||X-linked adrenal hypoplasia congenita
|3.||DAX-1 Orphan Nuclear Receptor
|4.||Steroidogenic Factor 1
|5.||Transcription Factors (Transcription Factor)
|6.||steroidogenic acute regulatory protein
|7.||Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)
|8.||Protein Kinase C
|9.||Gonadotropin-Releasing Hormone (GnRH)