Beta-sarcoglycanopathy

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Musculoskeletal Diseases: 719
- Muscular Diseases: 10128
  - Atrophic Muscular Disorders: 320
    - Muscular Dystrophies: 5779
      - Limb-Girdle Muscular Dystrophies: 800
        Beta-sarcoglycanopathy: 3
Nervous System Diseases: 14178
- Neuromuscular Diseases: 2005
  - Muscular Diseases: 10128
    - Atrophic Muscular Disorders: 320
      - Muscular Dystrophies: 5779
        Limb-Girdle Muscular Dystrophies: 800
        Beta-sarcoglycanopathy: 3
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Muscular Dystrophies: 5779
    - Limb-Girdle Muscular Dystrophies: 800
      - Beta-sarcoglycanopathy: 3

Related Diseases

1.	Sarcoglycanopathies
2.	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
3.	Cardiomyopathies (Cardiomyopathy)
4.	Muscular Dystrophies (Muscular Dystrophy)

Experts

1.	Angelini, Corrado: 2 articles (12/2014 - 12/2012)
2.	Tasca, Elisabetta: 2 articles (12/2014 - 12/2012)
3.	Fanin, Marina: 1 article (12/2014)
4.	Nascimbeni, Anna Chiara: 1 article (12/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Beta-sarcoglycanopathy:

1.	Sarcoglycans (beta Sarcoglycan)IBA 09/01/1999 - "To develop an animal model of beta-sarcoglycanopathy and to clarify the role of beta-sarcoglycan in the pathogenesis of the muscle degeneration in vivo, we developed beta-sarcoglycan-deficient mice using a gene targeting technique. " 12/01/2014 - "In sarcoglycanopathies, the sarcolemmal nNOS reactivity varied from absent to reduced, depending on the residual level of sarcoglycan complex: in cases with complete sarcoglycan complex deficiency (mostly in beta-sarcoglycanopathy), the sarcolemmal nNOS reaction was absent and it was always associated with early severe clinical phenotype and cardiomyopathy. " 12/01/2012 - "In Duchenne Muscular Dystrophy and beta-sarcoglycanopathy besides the alteration of dystrophin and/or sarcoglycan complex, a neuronal nitric oxide synthase depletion is frequently found and might correlate with post-exercise fatigability as well as with cardiac involvement. " 09/01/1999 - "beta-Sarcoglycan, one of the subunits of the sarcoglycan complex, is a transmembranous glycoprotein which associates with dystrophin and is the molecule responsible for beta-sarcoglycanopathy, a Duchenne-like autosomal recessive muscular dystrophy. "
2.	DystrophinIBA 12/01/2012 - "In Duchenne Muscular Dystrophy and beta-sarcoglycanopathy besides the alteration of dystrophin and/or sarcoglycan complex, a neuronal nitric oxide synthase depletion is frequently found and might correlate with post-exercise fatigability as well as with cardiac involvement. " 09/01/1999 - "beta-Sarcoglycan, one of the subunits of the sarcoglycan complex, is a transmembranous glycoprotein which associates with dystrophin and is the molecule responsible for beta-sarcoglycanopathy, a Duchenne-like autosomal recessive muscular dystrophy. "
3.	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 12/01/2012 - "In Duchenne Muscular Dystrophy and beta-sarcoglycanopathy besides the alteration of dystrophin and/or sarcoglycan complex, a neuronal nitric oxide synthase depletion is frequently found and might correlate with post-exercise fatigability as well as with cardiac involvement. "
4.	Glycoproteins (Glycoprotein)IBA 09/01/1999 - "beta-Sarcoglycan, one of the subunits of the sarcoglycan complex, is a transmembranous glycoprotein which associates with dystrophin and is the molecule responsible for beta-sarcoglycanopathy, a Duchenne-like autosomal recessive muscular dystrophy. "