Congenital torticollis

Inherited forms of torticollis that usually present at birth and may be accompanied by FACIAL ASYMMETRY. OMIM: 189600

Also Known As:

Congenital muscular torticollis; Familial spasmodic torticollis; Familial torticollis; Torticollis, congenital; Torticollis, familial

Networked: 94 relevant articles (17 outcomes, 12 trials/studies)

Relationship Network

Disease Context: Research Results

Signs and Symptoms Pathological Conditions
- Signs and Symptoms
  - Neurologic Manifestations: 7102
    - Dyskinesias: 7807
      - Dystonia: 5088
        Torticollis: 1463
        Congenital torticollis: 94

Related Diseases

1.	Torticollis (Wryneck)
2.	Fibrosis (Cirrhosis)
3.	Cleft Lip (Harelip)
4.	Nonsynostotic Plagiocephaly
5.	Velopharyngeal Insufficiency

Experts

1.	Kaplan, Sandra L: 4 articles (10/2020 - 01/2013)
2.	Greve, Kelly R: 3 articles (01/2022 - 01/2022)
3.	Rahlin, Mary: 2 articles (05/2022 - 01/2005)
4.	Oleszek, Joyce L: 2 articles (01/2020 - 10/2005)
5.	Coulter, Colleen: 2 articles (10/2018 - 01/2013)
6.	Sargent, Barbara: 2 articles (10/2018 - 01/2018)
7.	Park, Myong Chul: 2 articles (08/2018 - 08/2015)
8.	Liu, Yu-Jie: 2 articles (05/2018 - 02/2011)
9.	Wang, Jun-Liang: 2 articles (05/2018 - 02/2011)
10.	Kwon, Dong Rak: 2 articles (10/2014 - 08/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Congenital torticollis:

1.	Botulinum Toxins (Botulinum Toxin)IBA 09/01/2014 - "Effective treatment of congenital muscular torticollis using botulinum toxin." 11/01/2020 - "Botulinum toxin have been used to treat congenital muscular torticollis for the last 25 years; however, few studies have been published with only limited cases and short-term follow-up. " 11/01/2020 - "The results of our meta-analysis of single rate showed that the overall effective rate of botulinum toxin for congenital muscular torticollis was 84% (95% confidence interval [CI] 67%-96%). " 10/30/2010 - "Adult cases of congenital muscular torticollis successfully treated with botulinum toxin." 09/26/2006 - "Botulinum toxin injection for congenital muscular torticollis presenting in children and adults."
2.	Type A Botulinum Toxins (Botox)FDA Link 01/01/2023 - "Botulinum toxin type A outcomes in infants with refractory congenital muscular torticollis." 09/01/2016 - "Treatment with Botulinum Toxin Type A in Infants with Refractory Congenital Muscular Torticollis: A 10-Year Retrospective Study." 09/26/2006 - "Seven of eight pediatric and adult patients with congenital muscular torticollis were injected with botulinum toxin type A. " 02/01/2006 - "Botox has recently been shown to be an effective intermediate method of treatment for more resistant cases of congenital muscular torticollis. " 10/01/2005 - "Botulinum toxin type a in the treatment of children with congenital muscular torticollis."
3.	incobotulinumtoxinA FDA Link 01/01/2023 - "BoNT-A may be an effective and safe method for treatment in refractory cases of congenital muscular torticollis." 01/01/2023 - "The aim of this study was to determine the effectiveness of botulinum toxin type A (BoNT-A) injections in infants with congenital muscular torticollis (CMT) who were refractory to conservative management. " 01/01/2016 - "This case report examines the use of a custom neck orthosis following onabotulinumtoxinA (BoNT-A) injections for the treatment of congenital muscular torticollis (CMT) that has not been responsive to conservative treatment or previous injections. "
4.	Collagen Type III (Type III Collagen)IBA 11/03/2018 - "Expression of Bax/Bcl-2, TGF-β1, and Type III Collagen Fiber in Congenital Muscular Torticollis." 11/03/2018 - "BACKGROUND This study investigated the expression of Bax/Bcl-2, TGF-β1 and type III collagen fiber in sternocleidomastoid of congenital muscular torticollis (CMT), and explored the possible mechanisms of fibrosis in sternocleidomastoid of CMT. "
5.	ParaffinIBA 11/05/2021 - "Current studies in patients with congenital muscular torticollis (CMT) have predominantly focused on the role of tuina or paraffin therapy alone. " 11/05/2021 - "The electronic databases of PubMed, Cochrane Library, PsycINFO, EMBASE, the Chinese Scientific Journal Database, China National Knowledge Infrastructure, WanFang Data, Taiwan Electronic Periodical Services, and Web of Science will be searched from the inception to November 2021 using the following key terms: "Tuina," "traditional Chinese medicine massage," "paraffin," and "congenital muscular torticollis," for all relevant studies. " 11/05/2021 - "Chinese massage (Tuina) combline with paraffin therapy versus tuina or paraffin therapy alone for the treatment of congenital muscular torticollis: A protocol for systematic review and Bayesian network meta-analysis."
6.	14-thioglycolamido-7,8-dihydromorphinone (TAMO)IBA 01/01/2018 - "(2005) TAMO Therapy as a Major Component of Physical Therapy Intervention for an Infant With Congenital Muscular Torticollis: A Case Report. " 01/01/2005 - "The purpose of this case report is to describe the use of TAMO therapy in the physical therapy intervention for an infant with congenital muscular torticollis (CMT). " 01/01/2005 - "TAMO therapy as a major component of physical therapy intervention for an infant with congenital muscular torticollis: a case report."
7.	Therapeutic UsesIBA 08/01/2009 - "Therapeutic effect of microcurrent therapy in infants with congenital muscular torticollis."
8.	Prednisolone (Predate)FDA LinkGeneric 02/01/1963 - "[Treatment of congenital torticollis with prednisolone]."
9.	Analgesics (Analgesic Drugs)IBA 08/01/2018 - "Postoperative Analgesic Effect of Ultrasound-Guided Intermediate Cervical Plexus Block on Unipolar Sternocleidomastoid Release With Myectomy in Pediatric Patients With Congenital Muscular Torticollis: A Prospective, Randomized Controlled Trial."
10.	A-factor (Streptomyces)IBA 04/01/2013 - "The cervical range of motion as a factor affecting outcome in patients with congenital muscular torticollis."

Therapies and Procedures

1.	Physical Therapy Modalities (Physical Therapy Technique) 02/01/2014 - "Although the best treatment results in congenital torticollis are achieved during the first years of childhood, bipolar release of the SCM muscle followed by postsurgical physical therapy can be effective in neglected adult cases. " 05/01/2019 - "Physical therapy (PT) alone is not always effective for treatment of congenital muscular torticollis (CMT). " 01/01/2022 - "The purpose of this study is to describe infants with congenital muscular torticollis (CMT) who changed head presentation during an episode of physical therapy. " 12/01/2010 - "In this study, we developed a support vector regression model for congenital muscular torticollis to investigate the prognosis of the physical therapy treatent in infants. " 06/01/2010 - "The aim of the study was to evaluate the proportion of left and right congenital muscular torticollis (CMT) in both genders and age groups of the patients as well as to evaluate the duration of physical therapy and treatment outcome in observed population. "
2.	Therapeutics 06/01/1993 - "Recognition of cervical subluxation in patients with congenital muscular torticollis may help to explain residual head-neck posturing problems even after successful neck muscle therapy." 10/01/2014 - "Microcurrent therapy may increase the efficacy of therapeutic exercise with ultrasound for the treatment of congenital muscular torticollis involving the entire sternocleidomastoid muscle." 10/01/2014 - "Efficacy of microcurrent therapy in infants with congenital muscular torticollis involving the entire sternocleidomastoid muscle: a randomized placebo-controlled trial." 06/20/2023 - "Efficacy of Intensive Inpatient Therapy in Infants with Congenital Muscular Torticollis Involving the Entire Sternocleidomastoid Muscle." 10/01/2014 - "To compare the effects of a combination of therapeutic exercise and ultrasound with or without additional microcurrent therapy in infants with congenital muscular torticollis involving the entire sternocleidomastoid muscle. "
3.	Massage (Zone Therapy) 01/01/2019 - "The combination of massage and FSM, not previously reported, are tools that may be effective in congenital muscular torticollis treatment." 01/01/2022 - "Providing massage therapy in infants with congenital muscular torticollis is a safe and effective method to improve the cervical range of motion and function. " 08/28/2020 - "This study will provide an assessment of the current state of Chinese massage therapy for the congenital muscular torticollis, aiming to show the efficacy and safety of massage treatment. " 01/01/2022 - "To detect the effect and safety of massage therapy on infants with congenital muscular torticollis. " 01/01/2022 - "Effect of massage therapy on infants with congenital muscular torticollis: A retrospective comparative study."
4.	Injections 11/01/2020 - "Current evidence shows that botulinum toxin injections for the treatment of congenital muscular torticollis is safe and effective, with few serious adverse reactions. " 11/01/2020 - "The aim of the present study is to systematically review the effectiveness and safety of botulinum toxin injections for congenital muscular torticollis by analyzing these relevant literatures. " 11/01/2020 - "The authors searched PubMed, Web of Science, EMBASE, Cochrane Library, China Biology Medicine, for all articles about botulinum toxin injections for the congenital muscular torticollis. " 11/01/2020 - "The Effectiveness and Safety of Botulinum Toxin Injections for the Treatment of Congenital Muscular Torticollis." 10/01/2005 - "A total of 27 children with congenital muscular torticollis, 6-18 mos of age, received 30 botulinum toxin type A injections into their sternocleidomastoid or upper trapezius muscle, or both, at a pediatric tertiary care center between 1995 and 2001. "
5.	Conservative Treatment 10/01/2023 - "Surgical treatment of congenital muscular torticollis (CMT) has been proven clinically effective in cases that fail to normalize after conservative treatment, but reports on self-reported outcome and quality of life have been scarce. " 06/01/2015 - "Indications of pinless halo application included postoperative immobilization for congenital muscular torticollis in 38 cases, conservative management of atlantoaxial rotatory subluxation in 11 cases, postoperative immobilization following cervical fusion in 10 cases, and immobilization for occipital condyle fracture in 2 cases. " 11/01/2013 - "Conservative management of congenital muscular torticollis: an evidence-based algorithm and preliminary treatment parameter recommendations." 06/01/2012 - "Surgical correction of the congenital muscular torticollis (CMT) is recommended for patients with unsuccessful conservative treatment. " 11/01/2010 - "Surgical correction of the congenital muscular torticollis (CMT) is recommended for patients with unsuccessful conservative treatment. "