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9- chloro- 2- ethyl- 1- methyl- 3- (2,2,2- trifluoroethyl)- 3H- pyrrolo(3,2- f)quinolin- 7(6H)- one

an androgen receptor modulator; structure in first source

Also Known As:

LGD 3303; LGD-3303; LGD3303

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo(3,2-f)quinolin-7(6H)-one: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo(3,2-f)quinolin-7(6H)-one: 2

Experts

1.	Handa, R J: 1 article (06/2010)
2.	Kudwa, A E: 1 article (06/2010)
3.	López, F J: 1 article (06/2010)
4.	McGivern, R F: 1 article (06/2010)
5.	Burnett, Kelven: 1 article (02/2009)
6.	Chang, William Y: 1 article (02/2009)
7.	Chen, Yanling: 1 article (02/2009)
8.	Griffiths, Kimberly N: 1 article (02/2009)
9.	Hogue, Aimee: 1 article (02/2009)
10.	López, Francisco J: 1 article (02/2009)

Related Diseases

1.	Lordosis 06/01/2010 - "The current study investigated the action of a novel selective androgen receptor modulator (LGD-3303 [9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo-[3,2-f]quinolin-7(6H)-one]) on male-directed sexual preference, proceptivity, and lordosis behavior of female rats. " 06/01/2010 - "LGD-3303 treatment increased lordosis and proceptivity behaviors in ovariectomized females primed with suboptimal doses of estradiol benzoate plus progesterone. "
2.	Osteoporosis 02/01/2009 - "Combination therapy with LGD-3303 and alendronate had additive effects and may potentially be a useful therapy for osteoporosis and frailty."
3.	Frailty 02/01/2009 - "Combination therapy with LGD-3303 and alendronate had additive effects and may potentially be a useful therapy for osteoporosis and frailty."

Related Drugs and Biologics

1.	Androgen Receptors (Androgen Receptor)
2.	Alendronate (Alendronate Sodium)
3.	Progesterone
4.	estradiol 3-benzoate (estradiol benzoate)

Related Therapies and Procedures

1.	Therapeutics