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raoulic acid
antiviral against Picornaviruses from Raoulia australis; structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
raoulic acid: 1
Experts
1.
Baek, S H
: 1 article (01/2009)
2.
Choi, H J
: 1 article (01/2009)
3.
Kwon, D H
: 1 article (01/2009)
4.
Lim, C H
: 1 article (01/2009)
5.
Song, J H
: 1 article (01/2009)
Related Diseases
1.
Human Influenza (Influenza)
01/01/2009 - "
Antiviral assay using cytopathic effect (CPE) reduction method showed that raoulic acid possessed strong antiviral activity against human rhinovirus 2 (HRV2) with a 50% inhibition concentration (IC(50)) value of less than 0.1mug/ml, human rhinovirus 3 (HRV3) with a IC(50) value of 0.19 microg/ml, coxsackie B3 (CB3) virus with IC(50) values of 0.33 microg/ml, coxsackie B4 (CB4) virus with IC(50) values of 0.40 microg/ml, and enterovirus 71 (EV71) virus with IC(50) values of less than 0.1 microg/ml. However, the compound did not possess antiviral activity against influenza A (Flu A/PR, Flu A/WS, H1N1) and B viruses at four concentrations ranging from 0.1 to 100 microg/ml.
"
Related Drugs and Biologics
1.
Antiviral Agents (Antivirals)