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wilforine

isolated from Tripterygium wilfordii; structure in first source

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ma, Shujie: 2 articles (12/2019 - 06/2017)
2.	Ma, Zhiqing: 2 articles (12/2019 - 06/2017)
3.	Zhang, Xing: 2 articles (12/2019 - 06/2017)
4.	Chang, Ying-Tzu: 1 article (06/2020)
5.	Chou, Che-Yi: 1 article (06/2020)
6.	Hung, Chin-Chuan: 1 article (06/2020)
7.	Lee, Kuo-Hsiung: 1 article (06/2020)
8.	Liao, Wei-Chieh: 1 article (06/2020)
9.	Lin, Yu-Chao: 1 article (06/2020)
10.	Morris-Natschke, Susan L: 1 article (06/2020)

Related Diseases

1.	Paralysis (Palsy) 12/11/2019 - "Connected with previous research studies, it can be concluded that wilforine affects the calcium signaling pathway by combining with RyR and IP3R, causing calcium dyshomeostasis, which results in insect paralysis and death."
2.	Poisoning 06/01/2017 - "Both light and electron microscope observations revealed that damage to the muscle cells increased with poisoning time in larvae and adults treated with the LC80 dose of wilforine. "
3.	Neoplasms (Cancer) 06/01/2020 - "In addition, wilforine re-sensitized MDR cancer cells to chemotherapeutic drugs. " 06/01/2020 - "These results suggest a novel future therapeutic strategy for MDR cancer using wilforine as an adjuvant treatment with chemotherapy." 06/01/2020 - "Wilforine resensitizes multidrug resistant cancer cells via competitive inhibition of P-glycoprotein."

Related Drugs and Biologics

1.	Calcium
2.	Member 1 Subfamily B ATP Binding Cassette Transporter

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)