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neurymenolide A

isolated from the red alga Neurymenia fraxinifolia; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Pyrones: 35
      - neurymenolide A: 1
Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - neurymenolide A: 1
  - Polyketides: 231
    - Macrolides: 4391
      - neurymenolide A: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Polyketides: 231
    - Macrolides: 4391
      - neurymenolide A: 1

Experts

1.	Bach, Stéphane: 1 article (02/2019)
2.	Baratte, Blandine: 1 article (02/2019)
3.	Bulinski, Jeannette Chloë: 1 article (02/2019)
4.	Cousseau, Arnaud: 1 article (02/2019)
5.	Delehouzé, Claire: 1 article (02/2019)
6.	Fant, Xavier: 1 article (02/2019)
7.	Feizbakhsh, Omid: 1 article (02/2019)
8.	Foll-Josselin, Béatrice: 1 article (02/2019)
9.	Mehiri, Mohamed: 1 article (02/2019)
10.	Motuhi, Sofia-Eléna: 1 article (02/2019)

Related Diseases

1.	Osteosarcoma (Osteogenic Sarcoma) 02/01/2019 - "Furthermore, we combined fluorescence microscopy and flow cytometry to demonstrate that treatment of U-2 OS osteosarcoma human cells with neurymenolide A could block cell division in prometaphase by inhibiting the correct formation of the mitotic spindle, which induced a mitotic catastrophe that led to necrosis and apoptosis. "
2.	Neoplasms (Cancer) 02/01/2019 - "The marine α-pyrone macrolide neurymenolide A was previously isolated from the Fijian red macroalga, Neurymenia fraxinifolia, and characterized as an antibacterial agent against antibiotic-resistant strains that also exhibited moderate cytotoxicity in vitro against cancer cell lines. "
3.	Necrosis 02/01/2019 - "Furthermore, we combined fluorescence microscopy and flow cytometry to demonstrate that treatment of U-2 OS osteosarcoma human cells with neurymenolide A could block cell division in prometaphase by inhibiting the correct formation of the mitotic spindle, which induced a mitotic catastrophe that led to necrosis and apoptosis. "

Related Drugs and Biologics

1.	Macrolides
2.	Anti-Bacterial Agents (Antibiotics)