Heparin Cofactor II

A sulfated plasma protein with a MW of approximately 66kDa that resembles ANTITHROMBIN III. The protein is an inhibitor of thrombin in plasma and is activated by dermatan sulfate or heparin. It is a member of the serpin superfamily.

Also Known As:

Heparin Co-Factor II; Heparin Cofactor 2; Leuserpin 2; Protease Inhibitor Leuserpin 2; Serpin D1; Heparin Co Factor II; Heparin cofactor II

Pharmalogical Action Categories:

Antithrombins
Serine Proteinase Inhibitors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Alpha-Globulins: 100
        Heparin Cofactor II: 153
  - Globulins: 3062
    - Serum Globulins: 553
      - Alpha-Globulins: 100
        Heparin Cofactor II: 153
  - Serpins: 906
    - Antithrombin Proteins: 6
      - Heparin Cofactor II: 153
- Peptides: 82426
  - Serpins: 906
    - Antithrombin Proteins: 6
      - Heparin Cofactor II: 153

mouse Serpind1 protein

Bio-Agent Context: Research Results