alpha-2-Antiplasmin

A member of the serpin superfamily found in plasma that inhibits the lysis of fibrin clots which are induced by plasminogen activator. It is a glycoprotein, molecular weight approximately 70,000 that migrates in the alpha 2 region in immunoelectrophoresis. It is the principal plasmin inactivator in blood, rapidly forming a very stable complex with plasmin.

Also Known As:

alpha 2 Antiplasmin; Serpin F2; alpha(2)-Plasmin Inhibitor; alpha-2 Antiplasmin; alpha 2 Plasmin Inhibitor; alpha 2-Plasmin Inhibitor

Pharmalogical Action Categories:

Antifibrinolytic Agents
Serine Proteinase Inhibitors

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - alpha-2-Antiplasmin: 177
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - alpha-2-Antiplasmin: 177
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Alpha-Globulins: 100
        alpha-2-Antiplasmin: 177
  - Globulins: 3062
    - Serum Globulins: 553
      - Alpha-Globulins: 100
        alpha-2-Antiplasmin: 177
  - Serpins: 906
    - alpha-2-Antiplasmin: 177
- Peptides: 82426
  - Serpins: 906
    - alpha-2-Antiplasmin: 177

human SERPINF2 protein

Bio-Agent Context: Research Results