HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

arginine-grafted bioreducible poly(disulfide amine)polymer

used for non-viral gene delivery systems

Also Known As:

ABP polymer

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - arginine-grafted bioreducible poly(disulfide amine)polymer: 3

Experts

1.	Kim, Sung Wan: 3 articles (01/2016 - 03/2012)
2.	Yun, Chae-Ok: 2 articles (01/2016 - 03/2012)
3.	Kim, Pyung-Hwan: 2 articles (08/2012 - 03/2012)
4.	Choi, Joung-Woo: 1 article (01/2016)
5.	Lee, Young Sook: 1 article (01/2016)
6.	Oh, Jung-Eun: 1 article (01/2016)
7.	Lee, Minhyung: 1 article (08/2012)
8.	Kim, Jaesung: 1 article (03/2012)
9.	Lee, Jung-Sun: 1 article (03/2012)
10.	Nam, Hye Yeong: 1 article (03/2012)

Related Diseases

1.	Hypoxia (Hypoxemia) 01/01/2016 - "The aim of our study was to evaluate the therapeutic potential of anti-fibrotic human Relaxin-expressing plasmid DNA with hypoxia response element (HRE) 12 copies (HR1) delivered by a dendrimer type PAM-ABP polymer G0 (HR1/G0) after MI on functional, hemodynamic, geometric, and cardiac extracellular matrix (ECM) remodeling in rats. "
2.	Neoplasms (Cancer) 03/28/2012 - "As an effort to overcome limits of adenovirus (Ad) as a systemic delivery vector for cancer therapy, we developed a novel system using oncolytic Ad plasmid DNA with two bioreducible polymers: arginine-grafted bioreducible poly(disulfide amine)polymer (ABP) and PEG5k-conjugated ABP (ABP5k) in expectation of oncolytic effect caused by progeny viral production followed by replication. "
3.	Type 2 Diabetes Mellitus (MODY) 08/20/2012 - "TSTA exendin-4 expression system with SP and ABP polymer has a potential gene therapy for the treatment of type 2 diabetes."

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	Dendrimers (Dendrons)
3.	Relaxin
4.	Polymers
5.	Exenatide (Byetta)
6.	tumor-associated transplantation antigen (TSTA)

Related Therapies and Procedures

1.	Therapeutics