3',4'-didemethylnobiletin

a urinary metabolite derived from nobiletin; has anti-inflammatory and antitumor activities; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	DiMarco-Crook, Christina: 1 article (04/2020)
2.	Du, Zheyuan: 1 article (04/2020)
3.	Li, Zhengze: 1 article (04/2020)
4.	Rakariyatham, Kanyasiri: 1 article (04/2020)
5.	Wu, Xian: 1 article (04/2020)
6.	Xiao, Hang: 1 article (04/2020)
7.	Zheng, Jinkai: 1 article (04/2020)
8.	Chan, Kok Gan: 1 article (06/2019)
9.	Goh, Bey-Hing: 1 article (06/2019)
10.	Goh, Joanna Xuan Hui: 1 article (06/2019)

1.	Neoplasms (Cancer) 06/21/2019 - "Not only does nobiletin itself exhibit anti-cancer properties, but its derivatives are also promising chemopreventive agents; examples of derivatives with anti-cancer activity include 3'-demethylnobiletin (3'-DMN), 4'-demethylnobiletin (4'-DMN), 3',4'-didemethylnobiletin (3',4'-DMN) and 5-demethylnobiletin (5-DMN). "
2.	Colonic Neoplasms (Colon Cancer) 04/01/2020 - "Synergistic anticancer effects of curcumin and 3',4'-didemethylnobiletin in combination on colon cancer cells." 04/01/2020 - "Herein, for the first time, we studied the combination of curcumin and 3',4'-didemethylnobiletin (DDMN), a primary metabolite of nobiletin, to determine their combinatory effects in inhibiting growth of human colon cancer cells. "