E coli 2- succinyl- 5- enolpyruvyl- 6- hydroxy- 3- cyclohexadiene- 1- carboxylate synthase
a thiamine diphosphate and metal-ion-dependent enzyme that catalyzes the Stetter-like conjugate addition of alpha-ketoglutarate with isochorismate to release 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate and carbon dioxide; has been sequenced
Also Known As:
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase, E coli; MenD protein, E coli
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Bio-Agent Context: Research Results