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(diaminocyclohexane)(demethylcantharidin)platinum(II)

has antineoplastic activity; structure in first source

Also Known As:

(DACH)-Pt-(DMC); Pt(DACH)(DMC)

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organoplatinum Compounds
    - (diaminocyclohexane)(demethylcantharidin)platinum(II): 2

Experts

1.	Au-Yeung, Steve C F: 2 articles (11/2008 - 03/2006)
2.	Ho, Yee-Ping: 2 articles (11/2008 - 03/2006)
3.	Pang, Siu-Kwong: 2 articles (11/2008 - 03/2006)
4.	Yu, Chun-Wing: 2 articles (11/2008 - 03/2006)
5.	Guan, Huaji: 1 article (11/2008)
6.	Li, Kay K W: 1 article (03/2006)

Related Diseases

1.

Colorectal Neoplasms (Colorectal Cancer)

11/01/2008 - "To ascertain the mechanistic contribution of the DMC component, microarray analysis was conducted to compare the effect of the novel (R,R-DACH)-Pt-(DMC) complex and oxaliplatin, on the gene expression of human colorectal cancer (HCT116) cells. "
03/15/2006 - "Flow cytometric analysis revealed that the trans-DACH-Pt-DMC analogues showed similar behavior to oxaliplatin on affecting the cell cycle of the HCT116 colorectal cancer cell line, but distinct from that of cisplatin or carboplatin. "

Related Drugs and Biologics

1.	Oxaliplatin (Eloxatin)
2.	Carboplatin (JM8)
3.	Cisplatin (Platino)