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1- (6,6- bis(4- fluorophenyl)hexyl)- 4- (3,4,5- trimethoxybenzyl)piperazine

antagonist of above calcium channels

Also Known As:

NP 078585; NP-078585; NP078585

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - 1-(6,6-bis(4-fluorophenyl)hexyl)-4-(3,4,5-trimethoxybenzyl)piperazine: 2

Experts

1.	Belardetti, Francesco: 2 articles (06/2012 - 05/2010)
2.	Ding, Yanbing: 1 article (06/2012)
3.	Dong, Haiheng: 1 article (06/2012)
4.	Feng, Zhong-Ping: 1 article (06/2012)
5.	Hendricson, Adam: 1 article (06/2012)
6.	Jiang, Xinpo: 1 article (06/2012)
7.	Mitscher, Lester A: 1 article (06/2012)
8.	Pajouhesh, Hassan: 1 article (06/2012)
9.	Pajouhesh, Hossein: 1 article (06/2012)
10.	Porreca, Frank: 1 article (06/2012)

Related Diseases

1.

05/01/2010 - "In animal models, the N-type blocker and pain-reducing NP078585 is efficacious against key elements of ethanol dependency, including self-administration and relapse. "
06/15/2012 - "We previously reported the small organic N-type calcium channel blocker NP078585 that while efficacious in animal models for pain, exhibited modest L-type calcium channel selectivity and substantial off-target inhibition against the hERG potassium channel. "

Related Drugs and Biologics

1.	N-Type Calcium Channels (N-Type Calcium Channel)
2.	L-Type Calcium Channels (Dihydropyridine Receptor)
3.	Potassium Channels (Potassium Channel)
4.	Ethanol (Ethyl Alcohol)

Related Therapies and Procedures

1.	Self Administration (Administration, Self)