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prolyl-4-hydroxyproline

PHP in non-hydrolyzed morning urine may be marker in postmenopausal osteoporosis

Also Known As:

PHP dipeptide; prolyl-hydroxyproline

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - prolyl-4-hydroxyproline: 6

Experts

1.	Miao, Yu: 2 articles (10/2020 - 06/2018)
2.	Wu, Haohao: 2 articles (10/2020 - 06/2018)
3.	Zeng, Mingyong: 2 articles (10/2020 - 06/2018)
4.	Zhu, Suqin: 2 articles (10/2020 - 06/2018)
5.	Li, Duo: 1 article (10/2020)
6.	Wu, Lingyu: 1 article (10/2020)
7.	Zhang, Jiayou: 1 article (10/2020)
8.	Zhao, Yuanhui: 1 article (10/2020)
9.	Feng, Guangxin: 1 article (06/2018)
10.	Huang, Min: 1 article (06/2018)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 10/21/2020 - "This study aims to investigate the therapeutic effectiveness of porcine collagen hydrolysate (CH) and its underlying mechanism in the treatment of renal anemia by using adenine-induced CKD mice, RAW264.7 macrophages, and HepG2 hepatoma cells, with prolyl-hydroxyproline as a reference compound for collagen-derived hydroxyproline-containing di-/tripeptides. "
2.	Anemia 10/21/2020 - "This study aims to investigate the therapeutic effectiveness of porcine collagen hydrolysate (CH) and its underlying mechanism in the treatment of renal anemia by using adenine-induced CKD mice, RAW264.7 macrophages, and HepG2 hepatoma cells, with prolyl-hydroxyproline as a reference compound for collagen-derived hydroxyproline-containing di-/tripeptides. "
3.	Postmenopausal Osteoporosis 01/01/2008 - "Prolyl-hydroxyproline dipeptide in non-hydrolyzed morning urine and its value in postmenopausal osteoporosis."
4.	Osteoporosis 12/01/2017 - "Unhydrolyzed prolyl hydroxyproline (Pro-Hyp) and total 4-hydroxyproline (Hyp) in urine have been suggested as disease biomarkers for bone turnover and osteoporosis. "
5.	Muscular Atrophy (Muscle Atrophy) 11/05/2023 - "Preventive Effects of Collagen-Derived Dipeptide Prolyl-Hydroxyproline against Dexamethasone-Induced Muscle Atrophy in Mouse C2C12 Skeletal Myotubes." 11/05/2023 - "This research delves into the influence of Prolyl-hydroxyproline (Pro-Hyp), a collagen-derived peptide, on muscle atrophy induced with dexamethasone (DEX), a synthetic glucocorticoid, in mouse C2C12 skeletal myotubes. "

Related Drugs and Biologics

1.	Hydroxyproline (4 Hydroxyproline)
2.	Collagen
3.	Adenine
4.	Dipeptides
5.	Glycine (Aminoacetic Acid)
6.	Cytochromes b (Cytochrome b)
7.	Biomarkers (Surrogate Marker)
8.	Proline (L-Proline)
9.	Peptides (Polypeptides)
10.	Metals

Related Therapies and Procedures

1.	Therapeutics