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N- ((5- (3- (4,6- difluoro- 1H- benzimidazol- 2- yl)- 1H- indazol- 5- yl)- 4- methylpyridin- 3- yl)methyl)ethanamine

structure in first source

Also Known As:

AG 024322; AG-024322; AG024322

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - Indazoles: 179
        N-((5-(3-(4,6-difluoro-1H-benzimidazol-2-yl)-1H-indazol-5-yl)-4-methylpyridin-3-yl)methyl)ethanamine: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzimidazoles: 245
      - N-((5-(3-(4,6-difluoro-1H-benzimidazol-2-yl)-1H-indazol-5-yl)-4-methylpyridin-3-yl)methyl)ethanamine: 2
    - Indazoles: 179
      - N-((5-(3-(4,6-difluoro-1H-benzimidazol-2-yl)-1H-indazol-5-yl)-4-methylpyridin-3-yl)methyl)ethanamine: 2

Experts

1.	Bergqvist, Simon: 1 article (10/2016)
2.	Chen, Ping: 1 article (10/2016)
3.	Diehl, Wade: 1 article (10/2016)
4.	Ferre, Rose Ann: 1 article (10/2016)
5.	He, You-Ai: 1 article (10/2016)
6.	Hu, Wenyue: 1 article (10/2016)
7.	Lam, Hieu: 1 article (10/2016)
8.	Lee, Nathan V: 1 article (10/2016)
9.	Murray, Brion W: 1 article (10/2016)
10.	Nagata, Asako: 1 article (10/2016)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2016 - "Tumor cell studies of ATP-competitive CDK drugs (dinaciclib, AG-024322, abemaciclib, palbociclib, ribociclib) indicate similar pharmacology while analyses in untransformed cells illuminates significant differences. "
2.	Vascular System Injuries 11/01/2008 - "No deaths occurred and clinical signs of toxicity, including swelling at the IV administration site, were seen at > or =6 mg/kg. AG-024322 at > or =6 mg/kg produced pancytic bone marrow hypocellularity, lymphoid depletion, and vascular injury at the injection site. "

Related Drugs and Biologics

1.	Adenosine Triphosphate (ATP)
2.	dinaciclib
3.	palbociclib
4.	abemaciclib
5.	ribociclib