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24a-homo-1,15-dihydroxyergocalciferol

has antineoplastic activity; structure in first souce

Also Known As:

PRI 1907; PRI-1907; PRI1907

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Secosteroids: 22
      - Vitamin D: 33265
        Ergocalciferols: 700
        24a-homo-1,15-dihydroxyergocalciferol: 3
    - Cholestanes
      - Sterols: 2245
        Ergocalciferols: 700
        24a-homo-1,15-dihydroxyergocalciferol: 3
      - Cholestenes
        Ergocalciferols: 700
        24a-homo-1,15-dihydroxyergocalciferol: 3
Lipids: 114793
- Membrane Lipids: 1591
  - Sterols: 2245
    - Ergocalciferols: 700
      - 24a-homo-1,15-dihydroxyergocalciferol: 3

Experts

1.	Baurska, H: 1 article (08/2011)
2.	Chrobak, A: 1 article (08/2011)
3.	Kielbinski, M: 1 article (08/2011)
4.	Klopot, A: 1 article (08/2011)
5.	Kutner, A: 1 article (08/2011)
6.	Marcinkowska, E: 1 article (08/2011)
7.	Wijas, E: 1 article (08/2011)
8.	Filip, Beata: 1 article (10/2008)
9.	Kutner, Andrzej: 1 article (10/2008)
10.	Milczarek, Magdalena: 1 article (10/2008)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 08/01/2011 - "In addition, the analogs PRI-1906 and PRI-1907 were able to moderately inhibit proliferation and significantly activate expression of CYP24A1 mRNA in prostate cancer cells PC-3. "
2.	Neoplasms (Cancer) 11/01/1999 - "Analogues PRI-1906, PRI-1907, PRI-1909, PRI-2191, PRI-2192, PRI-2193 and PRI-2194 were examined for their antiproliferative activity in vitro against a spectrum of various human cancer cell lines using the MTT technique. "
3.	Breast Neoplasms (Breast Cancer) 10/01/2008 - "Toxicity and antitumor activity of the vitamin D analogs PRI-1906 and PRI-1907 in combined treatment with cyclophosphamide in a mouse mammary cancer model."

Related Drugs and Biologics

1.	1,25-dihydroxyergocalciferol
2.	Vitamin D3 24-Hydroxylase
3.	Vitamin D
4.	Messenger RNA (mRNA)
5.	Cyclophosphamide (Cytoxan)
6.	1 alpha,24-dihydroxyvitamin D3 (Tacalcitol)