Floxuridine FDA Link Generic

An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Also Known As:

FUdR; Fluorodeoxyuridine; 5 Fluorodeoxyuridine; 5-FUdR; 5-Fluorodeoxyuridine; Uridine, 2'-deoxy-5-fluoro-

Pharmalogical Action Categories:

Antimetabolites, Antineoplastic

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Uridine: 1186
        Deoxyuridine: 331
        Floxuridine: 690
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Uridine: 1186
      - Deoxyuridine: 331
        Floxuridine: 690
  - Deoxyribonucleosides: 34
    - Deoxyuridine: 331
      - Floxuridine: 690

5'-phenylalanyl-glycyl-floxuridine

Bio-Agent Context: Research Results