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aflibercept

has antiangiogenic activity; consists of the second and third Ig domains of VEGFR1 and VEGFR2, respectively, fusion to the Fc region of IgG1; putative antineoplastic agent that binds all VEGF-A isoforms; possible medicine for eye disorders
Also Known As:
AVE 0005; AVE 005; AVE-0005; AVE-005; AVE0005; AVE005; VEGF Trap - regeneron; VEGF Trap-Eye; VEGF-Trap; ZIV-aflibercept; Zaltrap; eylea
Networked: 1993 relevant articles (312 outcomes, 588 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Vitti, Robert: 39 articles (04/2022 - 06/2011)
2. Berliner, Alyson J: 33 articles (04/2022 - 11/2009)
3. Brown, David M: 30 articles (01/2022 - 06/2011)
4. Heier, Jeffrey S: 28 articles (05/2022 - 06/2011)
5. Wykoff, Charles C: 27 articles (01/2022 - 07/2014)
6. Chhablani, Jay: 25 articles (04/2021 - 05/2015)
7. Sivaprasad, Sobha: 23 articles (02/2022 - 09/2015)
8. Boyer, David S: 22 articles (01/2022 - 03/2013)
9. Yancopoulos, George D: 22 articles (09/2021 - 08/2002)
10. Kaiser, Peter K: 22 articles (01/2021 - 03/2012)

Related Diseases

1. Macular Edema
2. Macular Degeneration (Age-Related Maculopathy)
3. Colorectal Neoplasms (Colorectal Cancer)
4. Retinal Vein Occlusion
5. Polypoidal Choroidal Vasculopathy

Related Drugs and Biologics

1. Ranibizumab (Lucentis)
2. Bevacizumab (Avastin)
3. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
4. aflibercept
5. Retinaldehyde (Retinal)
6. Oxaliplatin (Eloxatin)
7. Dexamethasone (Maxidex)
8. Fluorouracil (Carac)
9. Irinotecan (Camptosar)
10. Leucovorin (Folinic Acid)

Related Therapies and Procedures

1. Therapeutics
2. Intravitreal Injections
3. Injections
4. Lasers (Laser)
5. Drug Therapy (Chemotherapy)