HT008-1

Nootropic and Neuroprotective Agents; Korean herbal medicine; contains roots of Panax ginseng, Acanthopanax senticosus, Angelica sinensis and Scutellaria baicalensis; in randomized, double-blind, placebo-controlled, trial 10/2008

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Bu, Youngmin: 2 articles (08/2010 - 01/2008)
2.	Choi, Hoyoung: 2 articles (08/2010 - 01/2008)
3.	Doré, Sylvain: 2 articles (08/2010 - 01/2008)
4.	Kim, Hocheol: 2 articles (08/2010 - 01/2008)
5.	Kim, Mi-Yeon: 2 articles (08/2010 - 01/2008)
6.	Kim, Yun Tai: 2 articles (08/2010 - 01/2008)
7.	Jamarkattel-Pandit, Nirmala: 1 article (08/2010)
8.	Kim, Jae Goo: 1 article (08/2010)
9.	Kim, Sung-Hoon: 1 article (08/2010)
10.	Kwon, Sungeun: 1 article (08/2010)

Related Diseases

1.	Stroke (Strokes) 08/01/2010 - "In conclusion, the results show that HT008-1 may be effective in a rat stroke model by an antiinflammatory mechanism and may improve sensory-motor function by reducing damage in the cortex and caudoputamen."
2.	Brain Ischemia (Cerebral Ischemia) 01/01/2008 - "The herbal mixture HT008-1 protects the most vulnerable CA1 pyramidal cells of the hippocampus and enhances spatial memory function against global brain ischemia; an anti-inflammatory effect may be one of the mechanisms of action." 01/01/2008 - "Neuroprotection and enhancement of spatial memory by herbal mixture HT008-1 in rat global brain ischemia model." 08/01/2010 - "The study investigated whether HT008-1 has neuroprotective effects in a focal cerebral ischemia rat model. " 08/01/2010 - "Neuroprotective effect of HT008-1, a prescription of traditional Korean medicine, on transient focal cerebral ischemia model in rats." 01/01/2008 - "To investigate whether HT008-1, a prescription used in traditional Korean medicine to treat mental and physical weakness, has a neuroprotective effect on a rat model of global brain ischemia and an enhancing effect against memory deficit following ischemia. "
3.	Ischemia 08/01/2010 - "HT008-1 (30, 100 and 300 mg/kg) and the component herbs (300 mg/kg) were administered orally twice at 0 and 2 h after ischemia. " 01/01/2008 - "HT008-1 was orally administered at doses of 30, 100, and 300 mg/kg respectively twice at 0 and 90 min after ischemia. " 01/01/2008 - "To investigate whether HT008-1, a prescription used in traditional Korean medicine to treat mental and physical weakness, has a neuroprotective effect on a rat model of global brain ischemia and an enhancing effect against memory deficit following ischemia. "
4.	Brain Infarction 08/01/2010 - "Oral administration of 300 mg/kg HT008-1 reduced brain infarction by 45.7%, prolonged the latency time by 24.8% in the rotarod test, and enhanced the score by 17.0% in the balance beam test. "
5.	Memory Disorders (Memory Loss) 01/01/2008 - "To investigate whether HT008-1, a prescription used in traditional Korean medicine to treat mental and physical weakness, has a neuroprotective effect on a rat model of global brain ischemia and an enhancing effect against memory deficit following ischemia. "

Related Drugs and Biologics

1.	Neuroprotective Agents

Related Therapies and Procedures

1.	Oral Administration