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(3- (4- (2(4- (4chloro- phenyl)- 3,6- dihydro- 2H- pyridin- 1- yl)- ethoxy)- phenyl)- (2S)- ethoxy- propionic acid)

exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo

Also Known As:

PAR-5359

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Propionates: 988
      - (3-(4-(2(4-(4chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl)-ethoxy)-phenyl)-(2S)-ethoxy-propionic acid): 1
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Propionates: 988
      - (3-(4-(2(4-(4chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl)-ethoxy)-phenyl)-(2S)-ethoxy-propionic acid): 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - (3-(4-(2(4-(4chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl)-ethoxy)-phenyl)-(2S)-ethoxy-propionic acid): 1

Experts

1.	Ahn, Byung-Nak: 1 article (10/2008)
2.	Bae, Myung-Ho: 1 article (10/2008)
3.	Chae, Yu Na: 1 article (10/2008)
4.	Choi, Hyun-Ho: 1 article (10/2008)
5.	Han, Taedong: 1 article (10/2008)
6.	Kim, Eunkyung: 1 article (10/2008)
7.	Kim, Jin Kwan: 1 article (10/2008)
8.	Kim, Mi-Kyung: 1 article (10/2008)
9.	Kim, Soon Hoe: 1 article (10/2008)
10.	Lee, Chun Ho: 1 article (10/2008)

Related Diseases

1.	Insulin Resistance 10/24/2008 - "In an insulin-resistant ob/ob mouse model, PAR-5359 significantly reduced plasma insulin levels, improved insulin sensitivity (HOMA-IR), and completely normalized plasma glucose levels. "
2.	Hepatocellular Carcinoma (Hepatoma) 10/24/2008 - "In functional assays using human mesenchymal stem cells and human hepatoma HepG2 cells, PAR-5359 significantly induced adipocyte differentiation and human ApoA1 secretion, which coincided with its transactivation potencies against the corresponding human receptor subtypes. "

Related Drugs and Biologics

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2.	Glucose (Dextrose)