aurilide

a 26-membered cyclodepsipeptide from the Japanese sea hare Dolabella auricularia; structure in first source

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

1.	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/28/2011 - "Results of the present study showed that aurilide selectively binds to prohibitin 1 (PHB1) in the mitochondria, activating the proteolytic processing of optic atrophy 1 (OPA1) and resulting in mitochondria-induced apoptosis. "
2.	Neoplasms (Cancer) 01/23/2021 - "Members of the aurilide family have shown to exhibit strong cytotoxicity against various cancer cell lines. " 05/01/2012 - "These compounds are structurally related to the aurilide-class of molecules, which have been reported to possess exquisite antiproliferative activities against cancer cells. " 01/28/2011 - "Prohibitin(g) cancer: aurilide and killing by Opa1-dependent cristae remodeling."

1.	Prohibitins