|1.||Wang, Liang: 3 articles (10/2011 - 06/2008)|
|2.||Zeng, Fuqing: 2 articles (03/2011 - 06/2008)|
|3.||Jiang, Guosong: 2 articles (03/2011 - 06/2008)|
|4.||Zheng, Jingfang: 1 article (02/2013)|
|5.||Wang, Yu: 1 article (02/2013)|
|6.||Yang, Fang: 1 article (02/2013)|
|7.||Liu, Peishu: 1 article (02/2013)|
|8.||Mao, Hong Luan: 1 article (02/2013)|
|9.||Zhang, Xiaolei: 1 article (02/2013)|
|10.||Pang, Yingxin: 1 article (02/2013)|
12/21/2000 - "This structural information, along with the binding data from BIR3 and Smac peptide mutants reported here, should aid in the design of small molecules that may be used for the treatment of cancers that overexpress IAPs."
05/01/2006 - "These results suggest that synthetic Smac peptide may be a new molecular targeting anti-tumor therapy for human glioblastoma."
07/01/2008 - "A novel polyarginine containing Smac peptide conjugate that mediates cell death in tumor and healthy cells."
02/15/2003 - "Our results indicate that IAP-dependent suppression of apoptosome predominantly occurs in IAP-overexpressing tumor, and the IAP-targeting Smac peptide is an effective molecule to increase tumor cell death induced by chemotherapy in vitro and in vivo."
|2.||Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/01/2003 - "Yang et al., Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide. "
02/15/2003 - "Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide."
|3.||Urinary Bladder Neoplasms (Bladder Cancer)
06/01/2008 - "The effects of synthetic Smac peptide (SmacN7) on chemotherapeutic sensitivity of bladder cancer cells were investigated. "
06/01/2008 - "Synthetic Smac peptide enhances chemo-sensitivity of bladder cancer cells."
10/01/2011 - "We combined MJ with the IAPs inhibitor, the second mitochondria-derived activator of caspases (Smac) peptide to treat bladder cancer cells. "
10/01/2011 - "Predominant enhancement of apoptosis induced by methyl jasmonate in bladder cancer cells: therapeutic effect of the Antp-conjugated Smac peptide."
|4.||Pancreatic Neoplasms (Pancreatic Cancer)
10/01/2007 - "Smac peptide enhanced TRAIL-induced apoptosis in a dose-dependent manner for several pancreatic cancer cell lines, but showed no effect on TRAIL-resistant AsPC-1 cells. "
10/01/2007 - "In various pancreatic cancer cell lines, TRAIL-induced apoptosis was evaluated in the presence or absence of an XIAP-inhibitor (Smac peptide). "
|5.||Ovarian Neoplasms (Ovarian Cancer)
|3.||Inhibitor of Apoptosis Proteins
|7.||NF-kappa B (NF-kB)
|8.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|10.||Etoposide (VP 16)
|1.||Drug Therapy (Chemotherapy)