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N- (17- (2- (4- isopropylthiazole- 2- yl)- 7- methoxy- 8- methylquinolin- 4- yloxy)- 13- methyl- 2,14- dioxo- 3,13- diazatricyclo(13.3.0.04,6)octadec- 7- ene- 4- carbonyl)(cyclopropyl)sulfonamide

inhibits HCV NS3/4A protease; structure in first source
Also Known As:
TMC 435; TMC 435350; TMC-435; TMC-435350; TMC435; TMC435350
Networked: 15 relevant articles (1 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lenz, Oliver: 6 articles (12/2015 - 03/2010)
2. Peeters, Monika: 4 articles (02/2014 - 01/2011)
3. Sekar, Vanitha: 4 articles (02/2014 - 01/2011)
4. Berg, Thomas: 3 articles (02/2014 - 01/2011)
5. De Smedt, Goedele: 3 articles (02/2014 - 06/2012)
6. Zeuzem, Stefan: 3 articles (02/2014 - 06/2012)
7. Hayashi, Norio: 2 articles (05/2015 - 01/2014)
8. Komada, Yuji: 2 articles (05/2015 - 01/2014)
9. Kato, Mai: 2 articles (05/2015 - 01/2014)
10. Goto, Shoichiro: 2 articles (05/2015 - 01/2014)

Related Diseases

1. Infection
2. Hepatitis C
3. Chronic Hepatitis C
4. Tuberculosis (Tuberculoses)
5. Fibrosis (Cirrhosis)

Related Drugs and Biologics

1. Protease Inhibitors (Protease Inhibitor)
2. MK-7009
3. N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamide
4. telaprevir
5. Ribavirin (Virazole)
6. Interferons
7. RNA (Ribonucleic Acid)
8. N- (17- (2- (4- isopropylthiazole- 2- yl)- 7- methoxy- 8- methylquinolin- 4- yloxy)- 13- methyl- 2,14- dioxo- 3,13- diazatricyclo(13.3.0.04,6)octadec- 7- ene- 4- carbonyl)(cyclopropyl)sulfonamide
9. Investigational Drugs
10. N- (2- fluoro- 4- (4- (2- (phenoxymethyl)- 1H- imidazol- 4- yl)phenoxy)phenyl)sulfamide