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valyl(2,2')-N-methylleucyl(5,5')- actinomycin D
has antineoplastic activity; structure in first source
Also Known As:
actinomycin D, valyl(2,2')-N-methylleucyl(5,5')-; (Val(2),MeLeu(5))(2)AMD; Leu(5)AMD; Leu5AMD; actinomycin D, Val(2,2')-N-methylLeu(5,5')-
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
3-Ring Heterocyclic Compounds
Dactinomycin: 2073
valyl(2,2')-N-methylleucyl(5,5')- actinomycin D: 1
Polycyclic Compounds: 6
Macrocyclic Compounds: 15
Cyclic Peptides: 530
Dactinomycin: 2073
valyl(2,2')-N-methylleucyl(5,5')- actinomycin D: 1
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Cyclic Peptides: 530
Dactinomycin: 2073
valyl(2,2')-N-methylleucyl(5,5')- actinomycin D: 1
Experts
1.
Li, Xinlei
: 1 article (09/2008)
2.
Wang, Kai-Rong
: 1 article (09/2008)
3.
Wang, Rui
: 1 article (09/2008)
4.
Yan, Jie-Xi
: 1 article (09/2008)
5.
Zhang, Bang-Zhi
: 1 article (09/2008)
6.
Zhang, Wei
: 1 article (09/2008)
Related Diseases
1.
Carcinoma (Carcinomatosis)
09/08/2008 - "
In the present study, an attempt has been made to investigate the effects of Leu5AMD on the proliferation of human gastric carcinoma cell line SGC-7901.
"
09/08/2008 - "
These results suggest that Leu5AMD may be used as a promising chemotherapeutical agent for patients affected by gastric carcinoma and other solid cancer.
"
2.
Sarcoma (Soft Tissue Sarcoma)
09/08/2008 - "
Treatment with Leu5AMD markedly suppressed the growth of Sarcoma xenograft.
"
3.
Neoplasms (Cancer)
09/08/2008 - "
These results suggest that Leu5AMD may be used as a promising chemotherapeutical agent for patients affected by gastric carcinoma and other solid cancer.
"