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lysyl-glutamyl-aspartyl-tryptophanamide

has homeostatic and endothelioprotective activities

Also Known As:

KEDW-NH2; Lys-Glu-Asp-Trp-NH2; pancragen

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - lysyl-glutamyl-aspartyl-tryptophanamide: 4

Experts

1.	Khavinson, V Kh: 4 articles (01/2015 - 10/2007)
2.	Goncharova, N D: 1 article (01/2015)
3.	Ivanova, L G: 1 article (01/2015)
4.	Oganyan, T E: 1 article (01/2015)
5.	Vengerin, A A: 1 article (01/2015)
6.	Durnova, A O: 1 article (02/2013)
7.	Kvetnaia, T V: 1 article (02/2013)
8.	Kvetnoy, I M: 1 article (02/2013)
9.	Linkova, N S: 1 article (02/2013)
10.	Polyakova, V O: 1 article (02/2013)

Related Diseases

1.	Diabetes Mellitus 10/01/2007 - "The results indicate homeostatic and endothelioprotective effects of pancragen during the early period of diabetes mellitus." 02/01/2013 - "Thus, transcription factors that regulate differentiation of pancreatic cells are a pharmacological target for pancragen, which allows considering it as an effective tool in the treatment of diabetes mellitus and pancreatitis." 10/01/2007 - "The effects of tetrapeptide pancragen (Lys-Glu-Asp-Trp-NH2) on blood glucose level and permeability and adhesion of mesenteric capillaries were studied in Wistar rats with experimental streptozotocin-induced diabetes mellitus. "
2.	Glucose Intolerance 01/01/2015 - "[Correction of impaired glucose tolerance using tetrapeptide (Pancragen) in old female rhesus monkeys]."
3.	Pancreatitis 02/01/2013 - "Thus, transcription factors that regulate differentiation of pancreatic cells are a pharmacological target for pancragen, which allows considering it as an effective tool in the treatment of diabetes mellitus and pancreatitis."
4.	Insulin Resistance 08/01/2011 - "Administration of the tetrapeptide pancragen is a promising approach to the correction of insulin resistance in elderly individuals." 08/01/2011 - "In patients with DM2, pancragen significantly decreased glucose level on an empty stomach and in standard glucose tolerance test and reduced plasma concentrations of insulin and insulin resistance index. "
5.	Experimental Diabetes Mellitus 10/01/2007 - "Effect of pancragen on blood glucose level, capillary permeability and adhesion in rats with experimental diabetes mellitus."

Related Drugs and Biologics

1.	Transcription Factors (Transcription Factor)
2.	Streptozocin (Streptozotocin)
3.	Insulin (Novolin)
4.	Glucose (Dextrose)
5.	Blood Glucose (Blood Sugar)