|1.||Eisenhofer, G: 2 articles (10/2009 - 02/2001)|
|2.||Pacak, K: 2 articles (10/2009 - 02/2001)|
|3.||Neumann, Hartmut P H: 2 articles (02/2008 - 03/2002)|
|4.||Kaelin, William G: 2 articles (01/2007 - 08/2005)|
|5.||Perren, A: 2 articles (08/2006 - 12/2005)|
|6.||Komminoth, P: 2 articles (08/2006 - 12/2005)|
|7.||Komminoth, Paul: 2 articles (01/2006 - 03/2005)|
|8.||Otremba, Mirek: 1 article (06/2015)|
|9.||Morel, Chantal F: 1 article (06/2015)|
|10.||Swallow, Carol: 1 article (06/2015)|
10/01/2005 - "In this study, we used direct sequencing to investigate VHL germline mutations in Korean patients with VHL disease or pheochromocytomas (11 VHL patients and 3 additional members from 7 families, 2 patients from 1 family with familial pheochromocytoma, and 2 cases of isolated pheochromocytoma). "
03/20/2005 - "We examined the value of SDHD mutation screening in patients presenting with apparently sporadic and familial pheochromocytoma for the identification of SDHD-related pheochromocytomas. "
12/01/2003 - "The molecular mechanisms involved in familial pheochromocytoma have been unraveled, but the detailed molecular mechanism of sporadic pheochromocytoma remains unknown. "
08/01/2003 - "Areas requiring further development include additional clinical experience with the measurement of plasma metanephrines that have been shown to have high sensitivity and specificity in the diagnosis of sporadic and familial pheochromocytoma, optimizing cost effectiveness of diagnostic imaging, improving the ability to predict and treat malignant pheochromocytoma, and elucidating not only the surgical approach but, perhaps with rapid advances in molecular genetics, ways of preventing familial pheochromocytoma."
07/01/2001 - "Although pheochromocytoma susceptibility may be associated with germline mutations in the tumor-suppressor genes VHL and NF1 and in the proto-oncogene RET, the genetic basis for most cases of nonsyndromic familial pheochromocytoma is unknown. "
08/01/2006 - "Similar observations in further patients should lead to a placebo-controlled study in patients with malignant or familial pheochromocytoma, or other tumors found to express the AT2 receptor."
12/01/1996 - "When all three studies were performed (n = 38), overall accuracy was 97% and only one extraadrenal tumor in a patient with familial pheochromocytoma was overlooked. "
01/01/2011 - "Although familial pheochromocytoma was found only in 6.7% of the patients, genetic testing should be considered in all patients, especially in patients with a family history, young age, or multifocal, bilateral, extra-adrenal, or malignant tumors. "
11/01/1986 - "In a case of malignant chromaffinoma, the adrenal was excised first which was diagnosed as a benign tumor by pathological examination. "
11/01/1986 - "It is difficult to diagnose malignant chromaffinoma among the endocrine tumors. "
12/01/2011 - "Although a large kindred with familial pheochromocytoma (Pheo) and paraganglioma (PGL) was discovered in 1962 and later found to represent von Hippel-Lindau (VHL) type 2A (mutation Y112H), the phenotype lacks current characterization. "
01/01/2006 - "In conclusion, these data indicate that germline mutations of SDHB and SDHC play a minor role in sporadic head and neck paraganglioma and further underline the importance of germline SDHB mutations in cases of familial pheochromocytoma-paraganglioma."
12/01/2004 - "The final diagnosis was familial pheochromocytoma/paraganglioma type 1 (OMIM 168000). "
08/01/1998 - "Laparoscopic adrenal sparing surgery (4 cases, 2 bilateral) and bilateral adrenalectomy (1) were performed for multiple familial pheochromocytoma, and all paragangliomas were excised simultaneously. "
09/01/2006 - "Logistic analysis showed that statistically significant risk factors for malignancy were (1) paraganglioma, (2) apparently sporadic, as opposed to familial, pheochromocytoma or paraganglioma, and (3) tumor size of > 6 cm. Surgical resection was performed for 28 patients (93%), with perioperative mortality and major morbidity rates of 0% and 10%, respectively. "
|4.||von Hippel-Lindau Disease (von Hippel Lindau Disease)
05/01/1979 - "Long-term epidemiological and laboratory studies were carried out in a kindred with familial pheochromocytoma associated with von Hippel-Lindau disease. "
06/23/1997 - "Familial pheochromocytoma due to mutant von Hippel-Lindau disease gene."
03/01/1996 - "Isolated familial pheochromocytoma as a variant of von Hippel-Lindau disease."
07/01/1995 - "Loss of heterozygosity on the short arm of chromosome 3 in sporadic, von Hippel-Lindau disease-associated, and familial pheochromocytoma."
10/06/1990 - "[Familial pheochromocytoma and Van Hippel-Lindau disease]."
|5.||Hypertension (High Blood Pressure)
09/01/2009 - "Hypercatecholaminemia manifestations are more common and pronounced when paroxysmal hypertension occurs, but persons with familial pheochromocytoma may be asymptomatic. "
09/01/2008 - "The present paper discusses the case of a patient with NF1 and periodic arterial hypertension in the course of unidentified chromaffinoma, which was complicated with myocardial infarction. "
09/01/2008 - "Chromaffinoma of the adrenal medulla (pheochromocytoma--PHEO) is a rare cause of arterial hypertension which is diagnosed incidentally or run in a family as a component of disease syndromes of the genetic origin. "
02/10/1975 - "Despite variable degrees of day-night differences, urinary excretion of VMA and metanephrines, per unit of time or per gram of urinary creatinine, was invariably higher in patients with pheochromocytoma than in controls whether the collection was 7 AM through 7 PM or 7 PM through 7 AM. Thus, shorter study periods are sufficient to exclude the presence of a chromaffinoma in most patients with hypertension."
01/01/1994 - "Vegetative dysfunction with episodes of tachycardia, hypertension, paleness, general hyperhidrosis, subfebrile condition, hyperglycemia manifest first among clinical symptoms of chromaffinoma. "
|2.||Succinate Dehydrogenase (Fumarate Reductase)
|5.||DNA (Deoxyribonucleic Acid)
|7.||Serotonin (5 Hydroxytryptamine)
|8.||Procollagen-Proline Dioxygenase (Prolyl Hydroxylase)
|10.||Membrane Proteins (Integral Membrane Proteins)