apratoxin D

a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Coltart, Don M: 1 article (10/2012)
2.	Robertson, Bradley D: 1 article (10/2012)
3.	Wengryniuk, Sarah E: 1 article (10/2012)
4.	Engene, Niclas: 1 article (06/2008)
5.	Gerwick, William H: 1 article (06/2008)
6.	Gutiérrez, Marcelino: 1 article (06/2008)
7.	Matainaho, Teatulohi: 1 article (06/2008)
8.	Suyama, Takashi L: 1 article (06/2008)
9.	Wingerd, Joshua S: 1 article (06/2008)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 10/19/2012 - "The first asymmetric total synthesis of the marine natural product apratoxin D, a highly potent inhibitor of H-460 human lung cancer cell growth (IC(50) value of 2.6 nM), is described. " 06/01/2008 - "Apratoxin D (1) showed potent in vitro cytotoxicity against H-460 human lung cancer cells with an IC 50 value of 2.6 nM."
2.	Neoplasms (Cancer) 06/01/2008 - "Cancer cell toxicity-guided fractionation of extracts of the Papua New Guinea marine cyanobacteria Lyngbya majuscula and Lyngbya sordida led to the isolation of apratoxin D (1). "