integrin alphaupsilonbeta6

plays an important role in the progression of colon cancer cells and a prognostic indicator for aggressive colon cancer in humans

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 09/15/2008 - "Supression of integrin alphaupsilonbeta6 inhibits the phosphorylation and nonphosphorylation level of ERK1/2, the secretion of uPA, pro-MMP-9 and pro-MMP-2 in tumor conditioned medium, and more important, inhibits MAPK-dependent [(3)H] labeled collagen IV degradation via the plasminogen activation cascade. "
2.	Colonic Neoplasms (Colon Cancer) 09/15/2008 - "Suppression of integrin alphaupsilonbeta6 by RNA interference in colon cancer cells inhibits extracellular matrix degradation through the MAPK pathway." 09/15/2008 - "Integrin alphaupsilonbeta6 plays a very important role in the progression of colon cancer cells and is now defined as a novel, independent prognostic indicator for aggressive colon cancer in humans. "

1.	Conditioned Culture Media
2.	Plasminogen
3.	Indicators and Reagents (Reagents)
4.	Collagen
5.	progelatinase