mucronulatol
compound from Caribbean propolis that exerts cytotoxic effects on human tumor cell lines
Also Known As:
3',7-dihydroxy-2',4'-dimethoxyisoflavan
Networked: 2
relevant articles (0 outcomes,
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Bio-Agent Context: Research Results
Experts
Related Diseases
| 1. | Neoplasms (Cancer)
05/01/2008
- " Here, we demonstrate for the first time that mucronulatol exerts cytotoxicity in cancer cell lines by targeting the control of cell cycle progression, indicating that the mechanism of action of this compound involves interference with the cell cycle machinery." 05/01/2008
- " This work aimed at initially characterizing the biological effects of mucronulatol in cancer cell lines comprehending both wildtype and resistant sublines. " 05/15/2008
- " Among the tested compounds, 7-hydroxy-6-methoxyflavanone (3) exhibited the most potent activity against B16-BL6 (IC(50), 6.66microM), LLC (IC(50), 9.29microM), A549 (IC(50), 8.63microM), and HT-1080 (IC(50), 7.94microM) cancer cell lines, and mucronulatol (26) against LLC (IC(50), 8.38microM) and A549 (IC(50), 9.9microM) cancer cell lines. "
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