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dolastatin 14
cytotoxic compound from sea hare, Dolabella auricularia; structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Macrocyclic Compounds: 15
Cyclic Peptides: 530
Depsipeptides: 297
dolastatin 14: 1
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Cyclic Peptides: 530
Depsipeptides: 297
dolastatin 14: 1
Experts
1.
Duffield, J J
: 1 article (04/2001)
2.
Pettit, G R
: 1 article (04/2001)
Related Diseases
1.
Neoplasms (Cancer)
04/01/2001 - "
Subsequent Wittig reaction with a phosphonium salt derived in three steps from tiglic acid gave (7S,15S)-dolatrienoic acid, one of the four possible diastereoisomers of the nonpeptide portion of the strong cancer cell growth inhibitory cyclodepsipeptide dolastatin 14 (1).
"
Related Drugs and Biologics
1.
Depsipeptides
2.
Salts
3.
Acids
4.
tiglic acid