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ingenane

from Euphorbia esula; structure in first source

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - ingenane: 7

Experts

1.	Behány, Zoltán: 1 article (06/2021)
2.	Dávid, Csilla Zsuzsanna: 1 article (06/2021)
3.	Hammadi, Reham: 1 article (06/2021)
4.	Hohmann, Judit: 1 article (06/2021)
5.	Kemény, Lajos: 1 article (06/2021)
6.	Kúsz, Norbert: 1 article (06/2021)
7.	Lakatos, Lóránt: 1 article (06/2021)
8.	Papp, László: 1 article (06/2021)
9.	Vasas, Andrea: 1 article (06/2021)
10.	Cai, Lu-Ying: 1 article (10/2017)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2001 - "The Euphorbia factors assayed exhibited moderate (H1) to low (H8) relative tumor-promoting potency in comparison to the ingenane prototype DTE tumor promoter 3-TI." 01/01/2001 - "V. Skin irriitant and tumor-promoting diterpene ester toxins of the tigliane and ingenane type in the herbs Euphorbia nubica and Euphorbia helioscopia contaminating fodder of livestock." 01/01/1998 - "I. Skin irritant and tumor-promoting ingenane-type diterpene esters in E. " 09/10/1999 - "A liquid chromatography-tandem mass spectrometry (LC-MS-MS) method was developed to detect tumor-promoting diterpene esters of the tigliane and ingenane types within plant extracts. "
2.	Actinic Keratosis 06/14/2021 - "Ingenol mebutate, isolated from Euphorbia peplus, is an ingenane-type diterpenoid, primarily used for the topical treatment of actinic keratosis, a premalignant skin condition. "
3.	Colorectal Neoplasms (Colorectal Cancer) 10/01/2017 - "Structure-activity relationship for 12 ingenane-type diterpenoids in colorectal cancer Colo205 cells were preliminary studied. "
4.	Dermatitis 09/01/1983 - "Five ingenane derivatives, 3-O-n-(deca-2,4,6-trienoyl)-16-O-[(Z)-2-methyl-2-butenoyl]-16-hydroxyingenol (1), 3-O-[(Z)-2-methyl-2-butenoyl]-5,16,20-O-triacetyl-16-hydroxyingenol (2), 3-O-[(Z)-2-methyl-2-butenoyl]-16,20-O-diacetyl-16-hydroxyingenol (3), 3-O-[(Z)-2-methyl-2-butenoyl]-20-O-acetylingenol (4), and 3-O-[(Z)-2-methyl-2-butenoyl]-16-O-acetyl-20-deoxy-16-hydroxyingenol (5) were isolated with a new procedure that uses droplet counter-current chromatography, from a dermatitis-producing fraction of the latex of Euphorbia hermentiana Lem. "
5.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 08/24/2023 - "Ingenane-type diterpenoids inhibit non-small cell lung cancer cells by regulating SRC/PI3K/Akt pathway."

Related Drugs and Biologics

1.	Diterpenes
2.	Esters
3.	Phorbols
4.	Plant Extracts
5.	Latex
6.	Irritants (Vesicants)
7.	Diacetyl (Biacetyl)
8.	Carcinogens
9.	3-ingenyl angelate