HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

2-amino-4-methylsulfanylbutyric acid 4- methoxy- 6- (4- methoxybenzylamino)- 2,2- dimethylchroman- 3- yl ester

a prolyl hydroxylase 2 activator; structure in first source

Also Known As:

KRH 102053; KRH-102053; KRH102053

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Butyrates: 2613
      - Aminobutyrates: 1253
        2-amino-4-methylsulfanylbutyric acid 4-methoxy-6-(4-methoxybenzylamino)-2,2-dimethylchroman-3-yl ester: 2
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Aminobutyrates: 1253
    - 2-amino-4-methylsulfanylbutyric acid 4-methoxy-6-(4-methoxybenzylamino)-2,2-dimethylchroman-3-yl ester: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - 2-amino-4-methylsulfanylbutyric acid 4-methoxy-6-(4-methoxybenzylamino)-2,2-dimethylchroman-3-yl ester: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - 2-amino-4-methylsulfanylbutyric acid 4-methoxy-6-(4-methoxybenzylamino)-2,2-dimethylchroman-3-yl ester: 2

Experts

1.	Gong, Young-Dae: 1 article (03/2011)
2.	Nepal, Manoj: 1 article (03/2011)
3.	Park, Young Ran: 1 article (03/2011)
4.	Soh, Yunjo: 1 article (03/2011)
5.	Choi, H J: 1 article (05/2008)
6.	Gong, Y-D: 1 article (05/2008)
7.	Gwak, W J: 1 article (05/2008)
8.	Soh, Y: 1 article (05/2008)
9.	Song, B-J: 1 article (05/2008)

Related Diseases

1.	Osteosarcoma (Osteogenic Sarcoma) 05/01/2008 - "The effects of KRH102053 on controlling HIF were studied in human HOS osteosarcoma, rat PC12 phaeochromocytoma and human HepG2 hepatoma cells. " 03/01/2011 - "KRH102140 more efficiently suppressed HIF-1α than KRH102053 in human osteosarcoma cells under hypoxia. "
2.	Hypoxia (Hypoxemia) 05/01/2008 - "Rapid degradation of hypoxia-inducible factor-1alpha by KRH102053, a new activator of prolyl hydroxylase 2." 03/01/2011 - "KRH102140 more efficiently suppressed HIF-1α than KRH102053 in human osteosarcoma cells under hypoxia. "
3.	Hepatocellular Carcinoma (Hepatoma) 05/01/2008 - "The effects of KRH102053 on controlling HIF were studied in human HOS osteosarcoma, rat PC12 phaeochromocytoma and human HepG2 hepatoma cells. "

Related Drugs and Biologics

1.	Prolyl Hydroxylases (Prolyl Hydroxylase)
2.	(2- fluorobenzyl)- (2- methyl- 2- phenyl- 2H- chromen- 6- yl- amine)