|1.||Lapchak, Paul A: 4 articles (05/2014 - 01/2011)|
|2.||Jayaraj, Richard L: 3 articles (09/2014 - 11/2013)|
|3.||Elangovan, Namasivayam: 3 articles (09/2014 - 11/2013)|
|4.||Manivasagam, Thamilarasan: 2 articles (09/2014 - 11/2013)|
|5.||Essa, Musthafa Mohamed: 1 article (09/2014)|
|6.||Dhanalakshmi, Chinnasamy: 1 article (09/2014)|
|7.||Ren, Jun: 1 article (05/2014)|
|8.||Nair, Sreejayan: 1 article (05/2014)|
|9.||Panzhinskiy, Evgeniy: 1 article (05/2014)|
|10.||Hua, Yinan: 1 article (05/2014)|
01/01/2011 - "In this study, we tested the efficacy of CNB-001 in a rigorous rabbit ischemic stroke model and determined the molecular basis of its in vivo activity. "
03/01/2011 - "For CNB-001, an estimated in vitro efficacy/toxicity ratio is 183-643-fold, suggesting that there is a significant therapeutic safety window for CNB-001 and that it should be further developed as a novel neuroprotective agent to treat stroke. "
01/01/2011 - "The novel multi-target curcuminoid, CNB-001, has a superior safety and pharmacokinetic profile and should be further developed as an acute monotherapy or to be used in conjunction with thrombolytics for acute ischemic stroke."
01/01/2011 - "On the basis of its in vivo efficacy and novel mode of action, we conclude that CNB-001 has a great potential for the treatment of ischemic stroke as well as other CNS pathologies."
01/01/2011 - "CNB-001 has substantial beneficial properties in an in vitro ischemia assay and improves the behavioral outcome of rabbit ischemic stroke even when administered 1 h after the insult, a therapeutic window in this model comparable to tissue plasminogen activator. "
|2.||Asthma (Bronchial Asthma)
08/01/2012 - "To advance the control of airway epithelial cell function and asthma, we investigated the effects of a new curcumin derivative, CNB001, which possesses improved pharmacological properties. "
08/01/2012 - "In conclusion, the curcumin derivative, CNB001, is a promising candidate to treat asthma associated with neutrophilic airway inflammation and remodeling."
08/01/2012 - "In addition, CNB001 significantly suppressed neutrophil infiltration, IL-6, TNF-α, IL-13 and active SERPINE1 production in bronchoalveolar lavage fluid of the murine asthma model, which was not observed in the case of DEX. "
05/01/2014 - "Taken together, CNB-001 alleviates obesity-induced glucose intolerance and represents a potential candidate for further development as an antidiabetic agent. "
05/01/2014 - "This study examined the effect of a novel neuroprotective curcuminoid, CNB-001 [4-((1E)-2-(5-(4-hydroxy-3-methoxystyryl-)-1-phenyl-1H-pyrazoyl-3-yl)vinyl)-2-methoxy-phenol], on glucose intolerance and insulin signaling in high-fat diet (HFD)-fed mice. "
|5.||Hepatocellular Carcinoma (Hepatoma)
|3.||Phenol (Carbolic Acid)
|6.||disufenton sodium (NXY 059)
|7.||Interleukin-6 (Interleukin 6)
|8.||Non-Receptor Type 1 Protein Tyrosine Phosphatase