majusculamide C
antineoplastic from marine sea hare Dolabella auricularia; structure in first source
Networked: 3
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Pettit, George R:
2 articles
(03/2008 - 07/2005)
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2. | Chapuis, Jean-Charles:
1 article
(03/2008)
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3. | Cichacz, Zbigniew:
1 article
(03/2008)
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4. | Craciunescu, Felicia:
1 article
(03/2008)
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5. | Cragg, Gordon M:
1 article
(03/2008)
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6. | Doubek, Dennis L:
1 article
(03/2008)
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7. | Du, Jiang:
1 article
(03/2008)
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8. | Goswami, Animesh:
1 article
(03/2008)
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9. | Herald, Cherry L:
1 article
(03/2008)
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10. | Hoard, Michael S:
1 article
(03/2008)
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Related Diseases
1. | Neoplasms (Cancer)
02/01/1996
- " For example, cryptophycin-1, a novel inhibitor of microtubule assembly from Nostoc sp GSV 224, shows impressive activity against a broad spectrum of solid tumors implanted in mice, including multidrug-resistant ones, and majusculamide C, a microfilament-depolymerizing agent from Lyngbya majuscula, shows potent fungicidal activity and may have use in the treatment of resistant fungal-induced diseases of domestic plants and agricultural crops." 07/01/2005
- " Twenty analogues of the natural antitumor agent dolastatin 11, including majusculamide C, were synthesized and tested for cytotoxicity against human cancer cells and stimulation of actin polymerization. " 03/01/2008
- " The isolation of interesting and valuable cancer cell growth inhibitors including majusculamide C ( 1), axinastatin 5 ( 5), bengazoles A ( 6), B ( 7), and E ( 8), manzamine A ( 10), jaspamide ( 11), and neoechinulin A ( 19) has been summarized."
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