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epimedin A

Also Known As:

anhydroicaritin 3-glucosyl-1-3-rhamnoside-7-glucoside

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        epimedin A: 4
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        epimedin A: 4

Experts

1.	Ahmed, Nehad J: 1 article (05/2022)
2.	Alahmari, Abdullah K: 1 article (05/2022)
3.	Almalki, Ziyad S: 1 article (05/2022)
4.	Alshehri, Ahmed M: 1 article (05/2022)
5.	Balaha, Mohamed F: 1 article (05/2022)
6.	Hamad, Abubaker M: 1 article (05/2022)
7.	Soliman, Gamal A: 1 article (05/2022)
8.	Bi, Yanan: 1 article (01/2021)
9.	Chai, Lijuan: 1 article (01/2021)
10.	Huang, Juyang: 1 article (01/2021)

Related Diseases

1.	Allergic Contact Dermatitis 08/01/2022 - "Epimedin A ameliorates DNFB-induced allergic contact dermatitis in mice: Role of NF-κB/NLRP3-driven pyroptosis, Nrf2/HO-1 pathway, and inflammation modulation." 08/01/2022 - "The present study aimed to investigate the potential of epimedin A to ameliorate DNFB-induced allergic contact dermatitis (CD) and reveal its potential underlying mechanisms of action, emphasizing its role in modulating NF-κB/NLRP3, Nrf2/HO-1 pathways, and inflammation. "
2.	Inflammation (Inflammations) 08/01/2022 - "Epimedin A is a novel, hopeful, natural therapeutic agent for CD by modulating NF-κB/NLRP3, Nrf2 pathways, and inflammation." 08/01/2022 - "Epimedin A ameliorates DNFB-induced allergic contact dermatitis in mice: Role of NF-κB/NLRP3-driven pyroptosis, Nrf2/HO-1 pathway, and inflammation modulation." 08/01/2022 - "The present study aimed to investigate the potential of epimedin A to ameliorate DNFB-induced allergic contact dermatitis (CD) and reveal its potential underlying mechanisms of action, emphasizing its role in modulating NF-κB/NLRP3, Nrf2/HO-1 pathways, and inflammation. "
3.	Osteoporosis 01/27/2021 - "Development of epimedin A complex drugs for treating the osteoporosis." 06/01/2014 - "The developed method in this paper enables the separation, enrichment and analysis of micro-amount metabolite of epimedin A, and anti-osteoporosis activities in vivo of epimedin A and baohuoside I was simple and efficient screening resorting to zebrafish osteoporosis mode. " 06/01/2014 - "This article firstly established a new efficient method for screening anti-osteoporosis ingredients, which used two-dimensional zebrafish model combined with hyphenated chromatographic techniques to evaluate anti-osteoporosis activities of epimedin A and its metabolite baohuoside I. Adult zebrafish was used for metabolism of epimedin A in 0.5% DMSO, and LC-MS was used for analysis of the metabolite, which was captured by HPLC, and prednisolone-induced osteoporosis model of zebrafish was used to evaluate the anti-osteoporotic activities of trace amounts of epimedin A and baohuoside I. The results indicated that epimedin A and baohuoside I can prevent prednisolone-induced osteoporosis in zebrafish. " 10/01/2015 - "For osteoporosis rats, the hydrolysis rates of icariin, epimedin A, epimedin B, and epimedin C incubated with intestinal flora for 1 hour were reduced by 0.19, 0.26, 0.19, and 0.14, respectively, compared with that in sham rats. "
4.	Dermatitis 08/01/2022 - "Epimedin A dose-dependently ameliorated DNFB-induced CD, as revealed by the repression of the mice's scratching behavior, dermatitis score, ear thickness and weight, and ear tissue's histopathological changes, and area percent of collagen fibers induced by DNFB. "

Related Drugs and Biologics

1.	Dinitrofluorobenzene
2.	Prednisolone (Predate)
3.	Dimethyl Sulfoxide (DMSO)
4.	Collagen
5.	epimedin C
6.	epimedin B
7.	baohuoside I
8.	icariin
9.	salicylhydroxamic acid (SHAM)