|1.||Woodward, Joshua J: 4 articles (02/2015 - 02/2011)|
|2.||Sauer, John-Demian: 4 articles (02/2015 - 02/2011)|
|3.||Vance, Russell E: 3 articles (06/2015 - 02/2011)|
|4.||Portnoy, Daniel A: 3 articles (01/2014 - 02/2011)|
|5.||Chin, Ko-Hsin: 2 articles (10/2015 - 08/2012)|
|6.||Chou, Shan-Ho: 2 articles (10/2015 - 08/2012)|
|7.||Huynh, TuAnh Ngoc: 2 articles (02/2015 - 09/2014)|
|8.||Tong, Liang: 2 articles (02/2015 - 09/2014)|
|9.||Bai, Guangchun: 2 articles (07/2014 - 02/2014)|
|10.||Bai, Yinlan: 2 articles (07/2014 - 02/2014)|
|1.||Human Influenza (Influenza)
01/01/2014 - "Intranasal delivery of influenza rNP adjuvanted with c-di-AMP induces strong humoral and cellular immune responses and provides protection against virus challenge."
01/01/2014 - "These results suggest that c-di-AMP is a potent mucosal adjuvant which may significantly contribute towards the development of innovative mucosal vaccines against influenza. "
01/01/2014 - "In this study we evaluate the protective efficacy of intranasal vaccination with recombinant influenza nucleoprotein (rNP) co-administrated with bis-(3',5')-cyclic dimeric adenosine monophosphate (c-di-AMP) as adjuvant. "
|3.||Pelvic Inflammatory Disease (Pelvic Inflammatory Diseases)
01/01/2013 - "During intracellular infection, increases in c-di-AMP production led to hyperactivation of the CSP. "
01/01/2010 - "MDR efflux pumps have also recently been shown to promote transport of cyclic diadenosine monophosphate (c-di-AMP) as a secreted molecule able to trigger a cytosolic host immune response following infection. "
04/01/2015 - "tuberculosis and that levels of c-di-AMP modulate the fate of infection. "
02/17/2015 - "monocytogenes mutant that lacks c-di-AMP phosphodiesterases exhibited elevated c-di-AMP levels, hyperinduced a host type-I IFN response, and was significantly attenuated for infection. "
09/11/2014 - "Cyclic di-adenosine monophosphate (c-di-AMP) is a broadly conserved second messenger required for bacterial growth and infection. "
|5.||Bites and Stings (Sting)
06/10/2015 - "monocytogenes short-circuits this pathway by producing the STING agonist, c-di-AMP. "
01/01/2013 - "We conclude that Chlamydia induces STING-mediated IFN responses through the detection of c-di-AMP in the host cell cytosol and propose that c-di-AMP is the ligand predominantly responsible for inducing such a response in Chlamydia-infected cells. "
01/01/2013 - "The failure to induce a type I IFN response to Chlamydia and c-di-AMP correlated with the inability of STING to relocalize from the endoplasmic reticulum to cytoplasmic punctate signaling complexes required for IFN activation. "
01/01/2014 - "monocytogenes secretes cyclic diadenosine monophosphate (c-di-AMP) which activates the innate immune sensor STING leading to the expression of IFN-β and co-regulated genes. "
01/01/2013 - "We further provide evidence that the host cell employs an endoplasmic reticulum (ER)-localized cytoplasmic sensor, STING (stimulator of interferon [IFN] genes), to detect c-di-AMP synthesized by Chlamydia and induce a protective IFN response. "
|1.||Adenosine Monophosphate (AMP)
|4.||bis(3',5')-cyclic diguanylic acid
|7.||Interferon Type I
|8.||DNA (Deoxyribonucleic Acid)
|9.||Small Interfering RNA (siRNA)